HitPredict

Interactor 1: DCLK2 (Q8N568)
Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)
Gene: DCLK2

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 766 Hs			1 1343
+	Hs
		208287 DCX_HUMAN (6-354): 9.62e-138: 412: 66.94		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1038915 KCC2B_HUMAN (388-757): 1.89e-131: 407: 33.50		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1039019 KCC2G_HUMAN (388-753): 7.49e-133: 407: 34.87		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1039152 KCC2D_HUMAN (388-698): 3.75e-133: 405: 37.46		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		166625 DCLK1_HUMAN (1-744): 0: 675: 65.34		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Mm
		99901 KCC2A_MOUSE (388-699): 1.12e-132: 403: 37.98		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Mm
		99917 KCC2B_MOUSE (388-760): 1.59e-131: 403: 33.25		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Rn
		88547 KCC2A_RAT (388-699): 1.12e-132: 403: 37.98		D3ZCL8_RAT (16-1295): 0: 959: 99.06
+	Hs
		166533 DCLK1_HUMAN (1-744): 0: 675: 65.34		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Hs
		809463 PAK5_HUMAN (9-658): 4.64e-139: 428: 21.48		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		809414 M3K3_HUMAN (17-650): 4.69e-140: 427: 16.67		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		1040049 M3K3_HUMAN (17-650): 4.69e-140: 427: 16.67		IQGA2_HUMAN (216-848): 1.05e-121: 416: 14.05
+	Hs
		809299 KCC2G_HUMAN (388-753): 7.49e-133: 407: 34.87		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Mm
		515255 KCC2A_MOUSE (388-699): 1.12e-132: 403: 37.98		IQGA1_MOUSE (219-857): 1.15e-122: 420: 13.49
+	Hs
		598472 KCC2B_HUMAN (388-757): 1.89e-131: 407: 33.50		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Hs
		598473 KCC2G_HUMAN (388-753): 7.49e-133: 407: 34.87		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Hs
		598474 KCC2D_HUMAN (388-698): 3.75e-133: 405: 37.46		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21