HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	21182203
Identification Methods	cosedimentation through density gradient, affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1063 Hs			1 530
+	Hs
		123550 MYO1C_HUMAN (1-1063): 0: 1224: 100.00		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		318374 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		556943 MYH7_HUMAN (4-1060): 0: 1071: 27.38		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		1367679 MYO5A_HUMAN (8-1058): 0: 1038: 27.30		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		1367703 MYH4_HUMAN (5-1045): 0: 1036: 26.88		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		67566 MYH7B_HUMAN (8-1045): 0: 1035: 26.95		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		227756 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		395408 MYH6_HUMAN (4-1060): 0: 1052: 26.88		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		772936 MYH9_HUMAN (5-974): 0: 994: 29.37		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		397312 MYO5A_HUMAN (8-1058): 0: 1038: 27.30		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		395602 MYH9_HUMAN (5-974): 0: 994: 29.37		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		318237 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		404030 MYO7A_HUMAN (8-973): 0: 1057: 31.12		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		404534 MYH2_HUMAN (5-1045): 0: 1048: 27.02		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		123568 MYO1C_HUMAN (1-1063): 0: 1224: 100.00		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		625771 MYH9_HUMAN (5-974): 0: 994: 29.37		RXRA_HUMAN (13-502): 1.61e-119: 361: 25.71
+	Hs
		318249 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		227776 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		520482 MYO5A_HUMAN (8-1058): 0: 1038: 27.30		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		520447 MYO5B_HUMAN (46-959): 0: 971: 30.60		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59