HitPredict

Interactor 1: Q6PA16 (Q6PA16)
BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (RING-type E3 ubiquitin transferase BRAP2)
Gene: brap.S

Interactor 2: Q8UUZ4 (Q8UUZ4)
small monomeric GTPase (EC 3.6.5.2)
Gene: hras.L

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	14724641
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007265 - Ras protein signal transduction
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 585 Xl			1 189
+	Mm
		1222733 BRAP_MOUSE (1-585): 0: 694: 78.85		RASH_MOUSE (16-189): 1.15e-71: 216: 95.98
+	Hs
		374711 BRAP_HUMAN (1-585): 0: 691: 80.24		RASH_HUMAN (16-189): 1.15e-71: 216: 95.98
+	Hs
		374090 UBP33_HUMAN (295-583): 9.46e-57: 207: 16.37		RASN_HUMAN (1-188): 5.76e-89: 260: 86.70
+	Hs
		375763 UBP33_HUMAN (295-583): 9.46e-57: 207: 16.37		RASK_HUMAN (1-188): 1.44e-84: 249: 86.17
+	Hs
		539830 UBP33_HUMAN (295-583): 9.46e-57: 207: 16.37		RALA_HUMAN (4-168): 5.12e-59: 185: 54.22
+	Hs
		1430484 HDAC6_HUMAN (299-400): 5.12e-30: 128: 22.22		RAB1B_HUMAN (4-179): 5.85e-72: 217: 33.71
+	Hs
		959418 HDAC6_HUMAN (299-400): 5.12e-30: 128: 22.22		RAP1B_HUMAN (1-179): 4.66e-63: 194: 55.25
+	Hs
		539851 HDAC6_HUMAN (299-400): 5.12e-30: 128: 22.22		RALA_HUMAN (4-168): 5.12e-59: 185: 54.22
+	Hs
		967244 HDAC6_HUMAN (299-400): 5.12e-30: 128: 22.22		RRAS2_HUMAN (3-188): 2.1e-58: 183: 56.32