HitPredict

Interactor 1: WDR59 (Q6PJI9)
GATOR2 complex protein WDR59 (WD repeat-containing protein 59)
Gene: WDR59

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 974 Hs			1 2514
+	Hs
		1159062 RBBP7_HUMAN (43-334): 3.55e-61: 216: 20.46		NCOR2_HUMAN (1-2514): 0: 892: 100.00
+	Hs
		1450956 NLE1_HUMAN (3-88): 2.28e-17: 88.3: 7.78		NCOR2_HUMAN (1-2514): 0: 892: 100.00
+	Hs
		1387667 SNR40_HUMAN (268-503): 2.32e-17: 86.8: 8.71		NCOR2_HUMAN (1-2514): 0: 892: 100.00
+	Hs
		278423 TBL1R_HUMAN (138-485): 1.26e-42: 165: 12.74		NCOR1_HUMAN (1-2514): 4.08e-122: 435: 34.00
+	Xl
		1169457 TB1RA_XENLA (267-503): 1.25e-10: 67.2: 9.80		Q1W3Z6_XENLA (4-2514): 6.49e-144: 505: 51.90
+	Hs
		278401 SNR40_HUMAN (268-503): 2.32e-17: 86.8: 8.71		NCOR1_HUMAN (1-2514): 4.08e-122: 435: 34.00
+	Xl
		1274156 TB1RA_XENLA (267-503): 1.25e-10: 67.2: 9.80		NCOR1_XENLA (1-2514): 2.46e-123: 439: 31.70
+	Dm
		1377808 EBI_DROME (142-485): 3.05e-44: 173: 13.76		Q9VYK0_DROME (113-505): 6.07e-62: 238: 36.96
+	Mm
		1296649 TBL1R_MOUSE (134-485): 4.71e-43: 166: 12.60		Q8BK32_MOUSE (1-280): 1.2e-40: 154: 49.66
+	Mm
		1296853 TBL1X_MOUSE (142-485): 8.82e-42: 163: 12.89		Q8BK32_MOUSE (1-280): 1.2e-40: 154: 49.66
+	Hs
		1158970 RBBP7_HUMAN (43-334): 3.55e-61: 216: 20.46		MINT_HUMAN (1652-2514): 4.81e-14: 81.2: 7.75
+	Hs
		1380244 FBXW7_HUMAN (219-506): 2.83e-22: 104: 12.93		RCOR1_HUMAN (388-705): 4.32e-45: 173: 22.05
+	Hs
		965097 WDR5_HUMAN (180-471): 1.59e-45: 169: 14.62		KMT2C_HUMAN (679-1264): 3.96e-16: 88: 11.93
+	Hs
		1380165 FBXW7_HUMAN (219-506): 2.83e-22: 104: 12.93		PRR36_HUMAN (113-1287): 1.18e-23: 112: 9.87
+	Dm
		1481107 POC1_DROME (135-343): 4.26e-37: 146: 16.27		Q9VLS7_DROME (674-1534): 4.1e-09: 64.5: 13.10
+	Hs
		1403515 NLE1_HUMAN (3-88): 2.28e-17: 88.3: 7.78		MINT_HUMAN (1652-2514): 4.81e-14: 81.2: 7.75
+	Hs
		1387512 SNR40_HUMAN (268-503): 2.32e-17: 86.8: 8.71		MINT_HUMAN (1652-2514): 4.81e-14: 81.2: 7.75
+	Hs
		1066558 RBBP4_HUMAN (145-377): 1.33e-17: 88.4: 20.39		CABIN_HUMAN (722-1134): 2.26e-13: 78.9: 19.17
+	Dm
		1481069 MIO_DROME (21-223): 4.19e-20: 98.4: 9.57		Q9VLS7_DROME (674-1534): 4.1e-09: 64.5: 13.10