HitPredict

Interactor 1: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Interactor 2: Q7TN74 (Q7TN74)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: Ppp1r9a

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30562941, 20124353
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PDZ, PDZ~PDZ_5, PDZ~SAM_2
Common GO terms	GO:0003779 - actin binding GO:0007015 - actin filament organization GO:0019722 - calcium-mediated signaling GO:0030175 - filopodium GO:0030426 - growth cone and 1 others more... GO:0030864 - cortical actin cytoskeleton
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 817 Mm			1 1095
+	Rn
		204565 NEB2_RAT (1-817): 3.55e-116: 373: 98.90		NEB1_RAT (1-1095): 6.12e-117: 389: 94.34
+	Mm
		1247106 NEB2_MOUSE (1-817): 1.67e-114: 368: 100.00		DLG1_MOUSE (240-1035): 6.88e-59: 221: 12.18
+	Mm
		1223569 NEB2_MOUSE (1-817): 1.67e-114: 368: 100.00		DLG4_MOUSE (363-1033): 2.13e-56: 211: 12.40
+	Mm
		999788 NEB2_MOUSE (1-817): 1.67e-114: 368: 100.00		DLG3_MOUSE (296-1035): 6.63e-54: 205: 11.22
+	Mm
		1247086 NEB2_MOUSE (1-817): 1.67e-114: 368: 100.00		NEB2_MOUSE (1-827): 1.65e-48: 188: 44.91
+	Hs
		936482 NEB1_HUMAN (1-817): 6.85e-101: 338: 46.73		AFAD_HUMAN (408-1094): 1.98e-39: 162: 14.46
+	Mm
		1247159 NEB2_MOUSE (1-817): 1.67e-114: 368: 100.00		DLG2_MOUSE (400-609): 1.83e-30: 131: 21.03
+	Mm
		98405 NEB2_MOUSE (1-817): 1.67e-114: 368: 100.00		E9QPE7_MOUSE (588-1094): 2.78e-12: 73.6: 13.11
+	Mm
		1247146 NEB2_MOUSE (1-817): 1.67e-114: 368: 100.00		MYH9_MOUSE (590-1093): 2.07e-11: 70.6: 12.57
+	Rn
		204585 NEB2_RAT (1-817): 3.55e-116: 373: 98.90		MYH10_RAT (598-1093): 3.98e-09: 63.2: 11.71
+	Mm
		1211232 NEB2_MOUSE (1-817): 1.67e-114: 368: 100.00		MYH4_MOUSE (610-1091): 1.08e-09: 65: 11.99
+	Mm
		1223375 NEB2_MOUSE (1-817): 1.67e-114: 368: 100.00		MYH10_MOUSE (598-1093): 3.09e-09: 63.6: 11.71
+	Hs
		772970 NEB2_HUMAN (1-817): 4.8e-111: 359: 95.84		MYH9_HUMAN (590-1076): 2.47e-10: 67.1: 12.16
+	Mm
		1223590 ERBIN_MOUSE (40-585): 6.32e-42: 167: 13.73		DLG4_MOUSE (363-1033): 2.13e-56: 211: 12.40
+	Mm
		1197968 Q52KF7_MOUSE (267-734): 1.03e-40: 162: 15.34		DLG4_MOUSE (363-1033): 2.13e-56: 211: 12.40
+	Hs
		1006092 LRRC7_HUMAN (15-586): 7.55e-41: 164: 12.93		DLG4_HUMAN (363-1033): 2.1e-55: 207: 11.78
+	Hs
		1006087 DLG3_HUMAN (267-734): 3.47e-40: 161: 14.72		DLG4_HUMAN (363-1033): 2.1e-55: 207: 11.78
+	Hs
		1399275 LRRC7_HUMAN (15-586): 7.55e-41: 164: 12.93		NEB2_HUMAN (1-827): 2.41e-48: 187: 45.26
+	Dm
		118984 M9NFI9_DROME (265-816): 1.06e-53: 204: 34.47		PATJ_DROME (483-602): 1.21e-31: 135: 40.00