HitPredict

Interactor 1: CHM4 (Q8T0Q4)
Charged multivesicular body protein 4 (CHMP4) (ESCRT-III complex core component shrb) (Protein Shrub)
Gene: shrb

Interactor 2: Q9VRJ5 (Q9VRJ5)
Charged multivesicular body protein 2b (LD36173p)
Gene: CHMP2B

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0000815 - ESCRT III complex GO:0005771 - multivesicular body GO:0032509 - endosome transport via multivesicular body sorting pathway
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 226 Dm			1 212
+	Hs
		92838 E9PSI1_HUMAN (1-202): 3.11e-57: 195: 55.07		CHM4B_HUMAN (14-207): 5e-32: 117: 16.00
+	Ce
		1090380 Q18886_CAEEL (1-226): 7.27e-48: 158: 55.51		Q9U2F6_CAEEL (2-196): 3.27e-41: 141: 30.26
+	Dm
		1249812 CHM4_DROME (1-226): 7.65e-50: 163: 100.00		Q95SH2_DROME (15-212): 9.22e-36: 126: 19.19
+	Dm
		1249815 CHM4_DROME (1-226): 7.65e-50: 163: 100.00		Q9VBI3_DROME (2-202): 3.45e-35: 126: 33.83
+	Ce
		1090378 Q18886_CAEEL (1-226): 7.27e-48: 158: 55.51		Q9GYK4_CAEEL (5-210): 2.81e-36: 127: 28.64
+	Dm
		1249811 CHM4_DROME (1-226): 7.65e-50: 163: 100.00		CHM4_DROME (1-187): 8.35e-33: 119: 15.87
+	Dm
		1249819 CHM4_DROME (1-226): 7.65e-50: 163: 100.00		Q9VN02_DROME (5-211): 2.16e-31: 115: 25.34
+	Dm
		1249822 CHM4_DROME (1-226): 7.65e-50: 163: 100.00		CHMP5_DROME (2-193): 2.23e-31: 115: 14.07
+	Ce
		1090379 Q18886_CAEEL (1-226): 7.27e-48: 158: 55.51		Q9TXI3_CAEEL (15-210): 1.46e-32: 118: 17.35
+	At
		1013158 VP601_ARATH (4-217): 2.12e-41: 142: 19.91		VPS2B_ARATH (4-210): 1.28e-37: 131: 31.96
+	Hs
		208860 CHM4B_HUMAN (1-225): 9.83e-39: 135: 56.96		CHM2A_HUMAN (2-191): 6.14e-38: 132: 35.26
+	Hs
		1286698 CHM4C_HUMAN (1-226): 4.9e-42: 144: 48.50		CHM4B_HUMAN (14-207): 5e-32: 117: 16.00
+	At
		98407 F4JXR3_ARATH (4-217): 1.56e-41: 144: 17.05		VP241_ARATH (4-204): 1.66e-30: 113: 24.88
+	Hs
		1286687 CHM4C_HUMAN (1-226): 4.9e-42: 144: 48.50		CHM4A_HUMAN (2-208): 4.62e-30: 112: 14.29
+	At
		1322582 VP601_ARATH (4-217): 2.12e-41: 142: 19.91		VP241_ARATH (4-204): 1.66e-30: 113: 24.88
+	Hs
		1260663 CHMP7_HUMAN (3-221): 1.35e-37: 137: 23.71		CHM4B_HUMAN (14-207): 5e-32: 117: 16.00
+	Zm
		77175 B4FU00_MAIZE (4-213): 9.73e-40: 137: 20.74		B4FU00_MAIZE (2-199): 6.46e-32: 117: 12.90
+	Mm
		1322098 CHM4B_MOUSE (1-225): 8.64e-39: 135: 56.96		CHM4B_MOUSE (14-207): 4.35e-32: 117: 16.00
+	Hs
		1260658 CHMP7_HUMAN (3-221): 1.35e-37: 137: 23.71		CHM4A_HUMAN (2-208): 4.62e-30: 112: 14.29