HitPredict

Interactor 1: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Interactor 2: HDAC6 (Q9UBN7)
Protein deacetylase HDAC6 (EC 3.5.1.-) (E3 ubiquitin-protein ligase HDAC6) (EC 2.3.2.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35676659
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1025 Hs			1 1215
+	Hs
		773296 MYH10_HUMAN (242-1024): 1.66e-21: 103: 8.45		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		773060 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		776867 MYH11_HUMAN (124-786): 5.18e-12: 72.4: 11.57		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		1143293 PLEC_HUMAN (499-978): 3.11e-11: 70.1: 14.96		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		1277796 MYH14_HUMAN (595-972): 3.71e-09: 63.1: 14.89		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Mm
		1223386 MYH10_MOUSE (540-1024): 6.42e-15: 82.1: 10.20		HDAC6_MOUSE (1-1215): 0: 1350: 74.32
+	Hs
		1110093 PKHA5_HUMAN (318-1019): 2.96e-36: 151: 13.24		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		940996 PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51		HDAC4_HUMAN (405-873): 3.54e-147: 473: 36.51
+	Hs
		1109803 MRCKA_HUMAN (418-981): 1.19e-30: 133: 12.40		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		1110177 MYH2_HUMAN (125-1012): 6.38e-17: 88.6: 10.27		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		772785 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		773240 MYH10_HUMAN (242-1024): 1.66e-21: 103: 8.45		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		556850 MYH1_HUMAN (515-1019): 1.69e-12: 74.4: 13.23		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		556922 MYH7_HUMAN (558-1009): 8.37e-12: 72.1: 10.92		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		1109744 PLEC_HUMAN (499-978): 3.11e-11: 70.1: 14.96		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		772937 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		773088 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		HDAC5_HUMAN (33-471): 8.24e-146: 471: 32.48