HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: RPB11 (P52435)
DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit)
Gene: POLR2J

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31048545, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006366 - transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 117
+	Hs
		854466 WWP1_HUMAN (1-870): 0: 888: 58.38		RPB11_HUMAN (1-117): 1.88e-53: 164: 100.00
+	Sc
		757151 TOM1_YEAST (494-869): 6.11e-158: 514: 40.26		RPB11_YEAST (1-110): 4.2e-45: 144: 50.00
+	Sc
		655650 TOM1_YEAST (494-869): 6.11e-158: 514: 40.26		RPAC2_YEAST (13-110): 5.03e-33: 114: 33.33
+	Sc
		757132 RSP5_YEAST (16-376): 1.4e-39: 159: 18.39		RPB11_YEAST (1-110): 4.2e-45: 144: 50.00