HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 184
+	Hs
		125391 LEG9_HUMAN (1-355): 3.81e-147: 421: 100.00		RAP1A_HUMAN (1-184): 1.03e-69: 211: 95.11
+	Hs
		125370 LEG9_HUMAN (1-355): 3.81e-147: 421: 100.00		RAB14_HUMAN (4-178): 7.99e-69: 209: 33.52
+	Hs
		125372 LEG9_HUMAN (1-355): 3.81e-147: 421: 100.00		RAP2B_HUMAN (1-184): 1.47e-65: 200: 61.41
+	Hs
		125181 LEG9_HUMAN (1-355): 3.81e-147: 421: 100.00		RALA_HUMAN (4-168): 2.04e-54: 173: 51.52
+	Hs
		127310 LEG8_HUMAN (1-355): 1.79e-106: 316: 30.85		RAB14_HUMAN (4-178): 7.99e-69: 209: 33.52
+	Hs
		480761 LEG1_HUMAN (234-353): 4.62e-34: 124: 32.00		RAC1_HUMAN (1-184): 1.74e-77: 231: 27.55
+	Hs
		375154 LEG3_HUMAN (5-147): 7.97e-42: 148: 38.00		RASK_HUMAN (1-167): 6.29e-55: 174: 57.49
+	Hs
		374458 LEG7_HUMAN (224-354): 5.44e-41: 142: 37.04		RASH_HUMAN (1-167): 1.23e-55: 175: 57.49
+	Hs
		374352 LEG1_HUMAN (234-353): 4.62e-34: 124: 32.00		RASH_HUMAN (1-167): 1.23e-55: 175: 57.49