HitPredict

Interactor 1: NEK9 (Q8TD19)
Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)
Gene: NEK9

Interactor 2: MLP3A (Q9H492)
Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha)
Gene: MAP1LC3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

Property	Details
Experiments	24067654, 35044719, 20562859
Identification Methods	affinity chromatography technology, unspecified method, anti tag coimmunoprecipitation, phage display
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 979 Hs			1 121
+	Hs
		891234 NEK9_HUMAN (1-979): 0: 1056: 100.00		GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74
+	Hs
		1254372 NEK9_HUMAN (1-979): 0: 1056: 100.00		MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82
+	Hs
		306243 NEK9_HUMAN (1-979): 0: 1056: 100.00		GBRAP_HUMAN (7-121): 2.99e-52: 161: 30.44
+	Hs
		1254369 NEK9_HUMAN (1-979): 0: 1056: 100.00		MLP3C_HUMAN (1-120): 5.63e-51: 159: 59.17
+	Hs
		1254374 NEK9_HUMAN (1-979): 0: 1056: 100.00		GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05
+	Hs
		1027430 STK3_HUMAN (27-485): 6.35e-129: 400: 20.09		MLP3A_HUMAN (1-121): 4.19e-54: 167: 100.00
+	Hs
		891124 STK3_HUMAN (27-485): 6.35e-129: 400: 20.09		GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74
+	Hs
		1027423 STK3_HUMAN (27-485): 6.35e-129: 400: 20.09		MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82
+	Hs
		306153 STK3_HUMAN (27-485): 6.35e-129: 400: 20.09		GBRAP_HUMAN (7-121): 2.99e-52: 161: 30.44
+	Hs
		1023110 STK4_HUMAN (29-485): 3.87e-126: 393: 22.17		MLP3A_HUMAN (1-121): 4.19e-54: 167: 100.00
+	Hs
		1027422 STK3_HUMAN (27-485): 6.35e-129: 400: 20.09		MLP3C_HUMAN (1-120): 5.63e-51: 159: 59.17
+	Hs
		891118 STK4_HUMAN (29-485): 3.87e-126: 393: 22.17		GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74
+	Hs
		1027427 STK3_HUMAN (27-485): 6.35e-129: 400: 20.09		GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05
+	Hs
		1023105 STK4_HUMAN (29-485): 3.87e-126: 393: 22.17		MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82
+	Hs
		306146 STK4_HUMAN (29-485): 3.87e-126: 393: 22.17		GBRAP_HUMAN (7-121): 2.99e-52: 161: 30.44
+	Hs
		1023104 STK4_HUMAN (29-485): 3.87e-126: 393: 22.17		MLP3C_HUMAN (1-120): 5.63e-51: 159: 59.17
+	Hs
		1023108 STK4_HUMAN (29-485): 3.87e-126: 393: 22.17		GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05
+	Hs
		1299973 NEK1_HUMAN (52-311): 4.47e-61: 229: 42.31		MLP3A_HUMAN (1-121): 4.19e-54: 167: 100.00
+	Hs
		296420 STK10_HUMAN (58-308): 1.96e-31: 135: 30.47		MLP3A_HUMAN (1-121): 4.19e-54: 167: 100.00