HitPredict

Interactor 1: PAXI1 (Q6ZW49)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: PAXIP1

Interactor 2: SRRM1 (Q8IYB3)
Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein)
Gene: SRRM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16159877
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016363 - nuclear matrix
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1069 Hs			1 904
+	Mm
		1240223 PAXI1_MOUSE (592-1069): 8.7e-145: 462: 92.47		KMT2C_MOUSE (120-861): 2.47e-10: 66.9: 12.00
+	Mm
		1240222 PAXI1_MOUSE (592-1069): 8.7e-145: 462: 92.47		KMT2D_MOUSE (463-897): 9.77e-10: 65: 11.03
+	Hs
		1314699 ECT2_HUMAN (26-279): 1.6e-50: 195: 14.02		SRRM1_HUMAN (1-904): 1.53e-74: 264: 100.00
+	Hs
		161483 PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00		KMT2D_HUMAN (113-824): 1.73e-10: 67.3: 11.54
+	Hs
		1129633 PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00		MDC1_HUMAN (197-904): 2.34e-09: 63.8: 8.82
+	Hs
		1257080 PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00		KMT2C_HUMAN (286-894): 4.08e-09: 63.1: 9.67
+	Dm
		119679 M9PB30_DROME (180-621): 3.82e-28: 125: 10.47		Q9VU43_DROME (6-820): 5.38e-32: 136: 23.63
+	Hs
		1129752 ECT2_HUMAN (26-279): 1.6e-50: 195: 14.02		MDC1_HUMAN (197-904): 2.34e-09: 63.8: 8.82
+	Dm
		119660 M9PB30_DROME (180-621): 3.82e-28: 125: 10.47		M9PB30_DROME (94-665): 4.21e-11: 69.6: 9.73
+	Dm
		119668 M9PB30_DROME (180-621): 3.82e-28: 125: 10.47		Q9VC60_DROME (504-842): 6.91e-09: 61.7: 17.73
+	Hs
		161497 TOPB1_HUMAN (3-336): 9.35e-18: 91.2: 16.57		KMT2D_HUMAN (113-824): 1.73e-10: 67.3: 11.54
+	Hs
		1129668 TOPB1_HUMAN (3-336): 9.35e-18: 91.2: 16.57		MDC1_HUMAN (197-904): 2.34e-09: 63.8: 8.82
+	Mm
		1455913 PCLO_MOUSE (158-819): 1.37e-14: 81.2: 7.84		PCLO_MOUSE (113-900): 9.66e-12: 71.5: 10.90
+	Hs
		161491 KMT2C_HUMAN (162-646): 4.44e-10: 66.6: 10.07		KMT2D_HUMAN (113-824): 1.73e-10: 67.3: 11.54
+	Hs
		1129698 MDC1_HUMAN (183-870): 3.67e-10: 66.6: 7.05		CHAP1_HUMAN (463-892): 3.66e-10: 66.1: 13.90
+	Hs
		1129588 MDC1_HUMAN (183-870): 3.67e-10: 66.6: 7.05		MDC1_HUMAN (197-904): 2.34e-09: 63.8: 8.82