HitPredict

Interactor 1: ZN483 (Q8TF39)
Zinc finger protein 483 (Zinc finger protein with KRAB and SCAN domains 16)
Gene: ZNF483

Interactor 2: ZN215 (Q9UL58)
Zinc finger protein 215 (BWSCR2-associated zinc finger protein 2) (BAZ-2) (Zinc finger protein with KRAB and SCAN domains 11)
Gene: ZNF215

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SCAN~SCAN, zf-C2H2~zf-C2H2
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 744 Hs			1 517
+	Hs
		1078408 ZN483_HUMAN (1-744): 0: 811: 100.00		ZKSC8_HUMAN (1-517): 0: 538: 29.16
+	Hs
		563724 ZN483_HUMAN (1-744): 0: 811: 100.00		ZKSC1_HUMAN (1-517): 1.62e-144: 428: 27.62
+	Hs
		1257092 ZN483_HUMAN (1-744): 0: 811: 100.00		ZKSC4_HUMAN (8-517): 5.9e-143: 423: 26.57
+	Hs
		485184 ZN483_HUMAN (1-744): 0: 811: 100.00		ZSC22_HUMAN (347-516): 2.45e-80: 260: 42.44
+	Hs
		1257105 ZN483_HUMAN (1-744): 0: 811: 100.00		ZSC21_HUMAN (348-516): 6.08e-77: 251: 43.28
+	Hs
		1257094 ZN483_HUMAN (1-744): 0: 811: 100.00		ZKSC3_HUMAN (136-376): 1.9e-43: 163: 14.09
+	Hs
		1244153 ZN483_HUMAN (1-744): 0: 811: 100.00		ZN397_HUMAN (432-517): 4.35e-37: 145: 42.53
+	Hs
		563279 ZNF16_HUMAN (239-743): 0: 648: 42.36		ZNF7_HUMAN (161-517): 2.51e-82: 271: 27.74
+	Hs
		152715 ZN483_HUMAN (1-744): 0: 811: 100.00		ZN197_HUMAN (177-329): 4.4e-13: 74.2: 18.59
+	Hs
		485174 Q6P088_HUMAN (1-240): 1.3e-166: 481: 100.00		ZSC22_HUMAN (347-516): 2.45e-80: 260: 42.44
+	Hs
		67869 ZN724_HUMAN (160-388): 6.7e-53: 195: 14.96		ZKSC8_HUMAN (1-517): 0: 538: 29.16
+	Hs
		1158017 Q6P088_HUMAN (1-240): 1.3e-166: 481: 100.00		ZSC21_HUMAN (348-516): 6.08e-77: 251: 43.28
+	Hs
		983758 ZNF91_HUMAN (103-383): 1.33e-49: 190: 15.17		ZKSC8_HUMAN (1-517): 0: 538: 29.16
+	Hs
		549138 ZN250_HUMAN (170-744): 3.05e-134: 410: 42.78		ZN250_HUMAN (153-516): 1.49e-93: 297: 30.60
+	Hs
		64162 ZN726_HUMAN (159-546): 2.05e-139: 425: 29.50		ZN430_HUMAN (197-479): 1.24e-86: 279: 26.79
+	Hs
		565101 ZNF7_HUMAN (308-687): 8.17e-107: 342: 47.91		ZNF71_HUMAN (109-457): 6.01e-117: 355: 19.62
+	Hs
		549144 ZN250_HUMAN (170-744): 3.05e-134: 410: 42.78		ZN165_HUMAN (250-516): 2.35e-43: 162: 29.46
+	Hs
		477793 ZN888_HUMAN (308-741): 9.2e-123: 385: 47.17		Z354C_HUMAN (290-517): 1.32e-31: 130: 34.86
+	Hs
		64156 ZN726_HUMAN (159-546): 2.05e-139: 425: 29.50		ZN716_HUMAN (198-335): 9.5e-15: 78.5: 15.22