Interactor 1: CAST1 (Q8WTX7)
Cytosolic arginine sensor for mTORC1 subunit 1 (Cellular arginine sensor for mTORC1 protein 1) (GATS-like protein 3)
Gene: CASTOR1

Interactor 2: CAST1 (Q8WTX7)
Cytosolic arginine sensor for mTORC1 subunit 1 (Cellular arginine sensor for mTORC1 protein 1) (GATS-like protein 3)
Gene: CASTOR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.904

The method score is based on:

Property Details
Experiments 25416956, 26972053, 32296183, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ACT_7~ACT_7, ACT_7~Castor1_N, Castor1_N~Castor1_N
Common GO terms GO:0005829 - cytosol
GO:0034198 - cellular response to amino acid starvation
GO:0034618 - arginine binding
GO:0140299 - small molecule sensor activity
GO:0140311 - protein sequestering activity
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 329
Hs

1 329
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024