HitPredict

Interactor 1: UPK1A (O00322)
Uroplakin-1a (UP1a) (Tetraspanin-21) (Tspan-21) (Uroplakin Ia) (UPIa) (UPKa)
Gene: UPK1A

Interactor 2: SPB4 (P48594)
Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2)
Gene: SERPINB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 258 Hs			1 390
+	Hs
		209319 TSN6_HUMAN (8-258): 1.94e-57: 185: 15.94		SPB4_HUMAN (1-390): 0: 510: 100.00
+	Hs
		209315 TSN6_HUMAN (8-258): 1.94e-57: 185: 15.94		SPB3_HUMAN (1-390): 9.6e-176: 496: 91.80
+	Hs
		125976 UPK1A_HUMAN (24-258): 1.11e-50: 168: 100.00		SPB3_HUMAN (1-390): 9.6e-176: 496: 91.80
+	Hs
		839516 CD81_HUMAN (10-258): 8.78e-52: 170: 15.81		SPB9_HUMAN (1-390): 9.15e-166: 470: 45.15
+	Hs
		209321 TSN6_HUMAN (8-258): 1.94e-57: 185: 15.94		SPB8_HUMAN (1-390): 4.5e-152: 435: 44.64
+	Hs
		125952 UPK1A_HUMAN (24-258): 1.11e-50: 168: 100.00		AACT_HUMAN (4-390): 8.94e-140: 406: 33.08
+	Hs
		209341 TSN6_HUMAN (8-258): 1.94e-57: 185: 15.94		SPA12_HUMAN (4-390): 3.49e-126: 371: 30.16
+	Hs
		580367 TSN8_HUMAN (9-258): 3.67e-47: 158: 15.14		SPA12_HUMAN (4-390): 3.49e-126: 371: 30.16