Protein: RB27B
Ras-related protein Rab-27B (EC 3.6.5.2) (C25KG)

Gene: RB27B, RAB27B
Organism: Homo sapiens
Interactions: 40
UniProt ID: O00194

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
GO:0005525 - GTP binding
GO:0005770 - late endosome
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

126000

SYTL5
Synaptotagmin-like protein 5

7

20

High-throughput

0.967

High

126005

MELPH
Melanophilin

5

20

Small-scale

0.919

High

126003

SYTL4
Synaptotagmin-like protein 4

4

20

Small-scale

0.906

High

126009

SYTL2
Synaptotagmin-like protein 2

4

20

Small-scale

0.894

High

125994

SYTL3
Synaptotagmin-like protein 3

2

20

High-throughput

0.811

High

125999

MYRIP
Rab effector MyRIP

2

20

High-throughput

0.783

High

126012

RPH3L
Rab effector Noc2

2

20

High-throughput

0.783

High

126013

RP3A
Rabphilin-3A

2

20

High-throughput

0.783

High

125990

RB27A
Ras-related protein Rab-27A

2

16

High-throughput

0.776

High

125983

RAE1
Rab proteins geranylgeranyltransferase component A 1

3

20

High-throughput

0.765

High

125984

RAE2
Rab proteins geranylgeranyltransferase component A 2

3

20

High-throughput

0.765

High

125997

SYTL1
Synaptotagmin-like protein 1

4

20

Small-scale

0.692

High

125981

GBA1
Lysosomal acid glucosylceramidase

3

1

High-throughput

0.662

High

125992

SCRB2
Lysosome membrane protein 2

2

2

High-throughput

0.628

High

125979

RASH
GTPase HRas

1

19

High-throughput

0.618

High

125985

EPHA2
Ephrin type-A receptor 2

1

11

High-throughput

0.618

High

125987

CEAM6
Cell adhesion molecule CEACAM6

1

4

High-throughput

0.618

High

126008

GORS2
Golgi reassembly-stacking protein 2

2

5

High-throughput

0.606

High

125995

CC186
Coiled-coil domain-containing protein 186

2

2

High-throughput

0.574

High

125982

DESM
Desmin

1

3

High-throughput

0.536

High

125986

CCR1
C-C chemokine receptor type 1

1

5

High-throughput

0.536

High

126011

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

1

High-throughput

0.536

High

125991

CAV1
Caveolin-1

1

4

Small-scale

0.515

High

126004

DHRS6
Dehydrogenase/reductase SDR family member 6

1

0

High-throughput

0.513

High

125993

CAH9
Carbonic anhydrase 9

1

1

High-throughput

0.479

High

125998

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

125978

S22A2
Solute carrier family 22 member 2

1

2

High-throughput

0.445

High

126007

TX101
Testis-expressed protein 101

1

8

High-throughput

0.445

High

85213

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

2

Small-scale

0.437

High

104799

APRIO
Alternative prion protein

1

6

High-throughput

0.437

High

125980

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

High-throughput

0.437

High

125988

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.437

High

126001

AKAP1
A-kinase anchor protein 1, mitochondrial

1

9

High-throughput

0.437

High

126002

ESR2
Estrogen receptor beta

1

9

High-throughput

0.437

High

126010

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

125989

DHYS
Deoxyhypusine synthase

3

0

High-throughput

0.352

High

126006

CINP
Cyclin-dependent kinase 2-interacting protein

1

0

High-throughput

0.279

Low

126014

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

67518

MYH7B
Myosin-7B

1

0

High-throughput

0.232

Low

125996

NRM
Nurim

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025