Protein: RB27A
Ras-related protein Rab-27A (Rab-27) (EC 3.6.5.2) (GTP-binding protein Ram)

Gene: RB27A, RAB27A
Organism: Homo sapiens
Interactions: 94
UniProt ID: P51159

Gene Ontology (top 5):
GO:0001750 - photoreceptor outer segment
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
GO:0005525 - GTP binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

902293

MELPH
Melanophilin

10

20

Small-scale

0.975

High

902287

SYTL4
Synaptotagmin-like protein 4

10

20

Small-scale

0.975

High

902271

SYTL3
Synaptotagmin-like protein 3

6

20

Small-scale

0.948

High

902284

SYTL5
Synaptotagmin-like protein 5

6

20

Small-scale

0.948

High

902298

SYTL2
Synaptotagmin-like protein 2

5

20

Small-scale

0.925

High

902283

MYRIP
Rab effector MyRIP

3

20

Small-scale

0.843

High

902307

RP3A
Rabphilin-3A

2

20

High-throughput

0.811

High

902306

RPH3L
Rab effector Noc2

2

20

Small-scale

0.799

High

125990

RB27B
Ras-related protein Rab-27B

2

16

High-throughput

0.776

High

664852

RAE1
Rab proteins geranylgeranyltransferase component A 1

2

20

High-throughput

0.776

High

686562

RAE2
Rab proteins geranylgeranyltransferase component A 2

2

20

High-throughput

0.776

High

902308

MYO5A
Unconventional myosin-Va

2

16

Small-scale

0.768

High

902280

SYTL1
Synaptotagmin-like protein 1

8

20

Small-scale

0.755

High

463032

YES
Tyrosine-protein kinase Yes

1

3

High-throughput

0.691

High

902268

KS6A1
Ribosomal protein S6 kinase alpha-1

1

3

High-throughput

0.691

High

902277

UN13D
Protein unc-13 homolog D

3

7

Small-scale

0.642

High

123236

PDLI1
PDZ and LIM domain protein 1

1

5

High-throughput

0.618

High

164803

UN13B
Protein unc-13 homolog B

1

13

Small-scale

0.618

High

373843

RASN
GTPase NRas

1

19

High-throughput

0.618

High

374479

RASH
GTPase HRas

1

20

High-throughput

0.618

High

375303

RASK
GTPase KRas

1

20

High-throughput

0.618

High

400504

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.618

High

820610

CEAM6
Cell adhesion molecule CEACAM6

1

5

High-throughput

0.618

High

902294

OSBL8
Oxysterol-binding protein-related protein 8

1

9

High-throughput

0.618

High

402345

GBA1
Lysosomal acid glucosylceramidase

2

1

High-throughput

0.601

High

902286

PGTA
Geranylgeranyl transferase type-2 subunit alpha

2

9

High-throughput

0.601

High

902264

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

9

High-throughput

0.575

High

902281

NHLC2
NHL repeat-containing protein 2

2

0

High-throughput

0.559

High

710129

EPHA2
Ephrin type-A receptor 2

1

12

High-throughput

0.553

High

902260

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.541

High

902279

CSN6
COP9 signalosome complex subunit 6

1

2

High-throughput

0.541

High

123637

MYO1C
Unconventional myosin-Ic

1

16

High-throughput

0.536

High

124905

GTPB1
GTP-binding protein 1

1

3

High-throughput

0.536

High

131366

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

2

High-throughput

0.536

High

210729

KLK10
Kallikrein-10

1

9

High-throughput

0.536

High

291262

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.536

High

482861

TPM1
Tropomyosin alpha-1 chain

1

1

High-throughput

0.536

High

902256

COPB
Coatomer subunit beta

1

2

High-throughput

0.536

High

902258

SMD1
Small nuclear ribonucleoprotein Sm D1

1

1

High-throughput

0.536

High

902259

SMD3
Small nuclear ribonucleoprotein Sm D3

1

1

High-throughput

0.536

High

902267

SYK
Lysine--tRNA ligase

1

2

High-throughput

0.536

High

902288

MOCOS
Molybdenum cofactor sulfurase

1

1

High-throughput

0.536

High

902289

MYO19
Unconventional myosin-XIX

1

12

High-throughput

0.536

High

902266

Q149M6
Exophilin 5

2

2

Small-scale

0.533

High

902263

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

High-throughput

0.518

High

107299

F8VUA7
Oxysterol-binding protein

1

9

High-throughput

0.514

High

135108

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

0

High-throughput

0.513

High

351091

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.513

High

428093

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.513

High

902257

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.513

High

902291

ARP5L
Actin-related protein 2/3 complex subunit 5-like protein

1

0

High-throughput

0.513

High

902296

SH3L3
SH3 domain-binding glutamic acid-rich-like protein 3

1

0

High-throughput

0.513

High

902301

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.513

High

421745

A4
Amyloid-beta precursor protein

1

11

High-throughput

0.501

High

873849

PCP4
Calmodulin regulator protein PCP4

1

0

High-throughput

0.493

High

289466

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

2

High-throughput

0.489

High

838681

MTREX
Exosome RNA helicase MTR4

1

1

High-throughput

0.489

High

902272

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

3

High-throughput

0.489

High

902303

MRT4
mRNA turnover protein 4 homolog

1

1

High-throughput

0.489

High

458336

ADRB2
Beta-2 adrenergic receptor

1

2

Small-scale

0.481

High

563446

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

Small-scale

0.479

High

639111

SYT1
Synaptotagmin-1

1

19

Small-scale

0.479

High

902278

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

1

High-throughput

0.479

High

902297

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

902305

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

902299

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

902282

EXPH5
Exophilin-5

1

2

High-throughput

0.445

High

902295

OSBL6
Oxysterol-binding protein-related protein 6

1

8

High-throughput

0.445

High

228212

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

1

High-throughput

0.437

High

257786

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

1

High-throughput

0.437

High

902261

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.437

High

902265

RBM39
RNA-binding protein 39

1

8

High-throughput

0.437

High

902270

CAH9
Carbonic anhydrase 9

1

1

High-throughput

0.437

High

902300

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

782922

CH3L1
Chitinase-3-like protein 1

1

0

High-throughput

0.426

High

902269

SMN
Survival motor neuron protein

1

0

High-throughput

0.426

High

902275

RIF1
Telomere-associated protein RIF1

1

4

High-throughput

0.417

High

91507

C9IYT0
H/ACA ribonucleoprotein complex subunit DKC1

1

1

High-throughput

0.407

High

114435

H0Y4X3
RNA binding motif protein 39

1

7

High-throughput

0.407

High

114498

H0YCQ8
Eukaryotic translation initiation factor 3 subunit M

1

1

High-throughput

0.407

High

116282

H3BND3
Cleavage and polyadenylation specificity factor subunit 5

1

1

High-throughput

0.407

High

902285

LPAR1
Lysophosphatidic acid receptor 1

1

5

High-throughput

0.407

High

248387

GDF9
Growth/differentiation factor 9

1

0

High-throughput

0.282

High

902273

RBM48
RNA-binding protein 48

1

0

High-throughput

0.282

High

902302

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.282

High

902304

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

187034

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.279

Low

769681

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.279

Low

902262

GTF2I
General transcription factor II-I

1

0

High-throughput

0.279

Low

902276

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.279

Low

902290

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.279

Low

902292

RETNB
Resistin-like beta

1

0

High-throughput

0.279

Low

902274

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

332293

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025