HitPredict

Interactor 1: ASXL2 (Q76L83)
Putative Polycomb group protein ASXL2 (Additional sex combs-like protein 2)
Gene: ASXL2

Interactor 2: MBD5 (Q9P267)
Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5)
Gene: MBD5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	36180891, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1435 Hs			1 1494
+	Hs
		1312435 ASXL1_HUMAN (337-1435): 1.53e-13: 78.1: 12.18		MBD5_HUMAN (1-1494): 0: 2832: 100.00
+	Hs
		1421200 ASXL3_HUMAN (71-1435): 1.68e-11: 71.6: 11.39		MBD5_HUMAN (1-1494): 0: 2832: 100.00
+	Hs
		1260613 ASXL2_HUMAN (1-1435): 0: 646: 100.00		MBD6_HUMAN (1-133): 5.99e-47: 186: 55.97
+	Hs
		1312407 ASXL1_HUMAN (337-1435): 1.53e-13: 78.1: 12.18		MBD6_HUMAN (1-133): 5.99e-47: 186: 55.97
+	Hs
		1387738 ASXL3_HUMAN (71-1435): 1.68e-11: 71.6: 11.39		MBD6_HUMAN (1-133): 5.99e-47: 186: 55.97
+	Dm
		68968 ASX_DROME (1345-1433): 2.24e-16: 87.6: 30.56		MBD56_DROME (24-107): 1.66e-29: 130: 39.29