HitPredict

Interactor 1: EIF3M (Q7JVI3)
Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Transport and Golgi organization protein 7) (Tango-7)
Gene: EIF3M

Interactor 2: EI3F1 (Q9VN50)
Eukaryotic translation initiation factor 3 subunit F-1 (eIF3f-1) (Eukaryotic translation initiation factor 3 subunit 5-1)
Gene: eIF3f1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 37061542, 14605208, 22036573, unassigned2874, 38944040
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MitMem_reg~eIF3m_C_helix, MitMem_reg~PCI
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003743 - translation initiation factor activity
GO:0005852 - eukaryotic translation initiation factor 3 complex
GO:0016282 - eukaryotic 43S preinitiation complex
GO:0031369 - translation initiation factor binding
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 387
Dm

1 280
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Ce
+ Sp
+ Ce
+ Sp
+ Sc
+ Hs
+ Ce
+ Dm
+ Dm
+ At
+ At
+ Sp
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025