HitPredict

Interactor 1: ODPX (O00330)
Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)
Gene: PDHX

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29511261, 35915203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 501 Hs			1 2610
+	Hs
		506079 ODB2_HUMAN (1-500): 2.22e-155: 452: 24.56		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		739346 ODO2_HUMAN (19-500): 2.29e-128: 382: 22.93		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		489839 ODP2_HUMAN (11-277): 8.66e-33: 134: 21.50		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Sc
		581278 ODO2_YEAST (48-500): 5.43e-121: 364: 23.36		UFD4_YEAST (2031-2610): 2.7e-129: 448: 28.16
+	Sc
		520838 ODP2_YEAST (26-500): 3.04e-143: 421: 30.91		RSP5_YEAST (2265-2608): 2.06e-105: 360: 20.86
+	Mm
		1186490 ODO2_MOUSE (19-500): 4.08e-131: 389: 22.73		HUWE1_MOUSE (2405-2609): 1.01e-18: 96.7: 33.33
+	Hs
		489732 ODP2_HUMAN (11-277): 8.66e-33: 134: 21.50		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95