Protein: PTK6
Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)

Gene: PTK6
Organism: Homo sapiens
Interactions: 93
UniProt ID: Q13882

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0004713 - protein tyrosine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005102 - signaling receptor binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1046400

PTK6
Protein-tyrosine kinase 6

5

19

Small-scale

0.924

High

338406

EGFR
Epidermal growth factor receptor

3

20

Small-scale

0.840

High

601919

ERBB3
Receptor tyrosine-protein kinase erbB-3

3

20

Small-scale

0.840

High

383794

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

Small-scale

0.802

High

993249

ACTN3
Alpha-actinin-3

2

6

High-throughput

0.783

High

1028468

SLAP1
Src-like-adapter

2

18

High-throughput

0.783

High

1046406

ANR55
Ankyrin repeat domain-containing protein 55

2

7

High-throughput

0.783

High

441500

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

499266

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

1035373

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.692

High

1046415

DDX17
Probable ATP-dependent RNA helicase DDX17

4

2

High-throughput

0.681

High

130062

EXOC5
Exocyst complex component 5

3

1

High-throughput

0.675

High

991758

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

3

20

Small-scale

0.667

High

1046412

CCD33
Coiled-coil domain-containing protein 33

2

3

High-throughput

0.665

High

573257

TCPA
T-complex protein 1 subunit alpha

3

20

High-throughput

0.650

High

826655

TCPG
T-complex protein 1 subunit gamma

3

20

High-throughput

0.650

High

842865

TCPQ
T-complex protein 1 subunit theta

3

20

High-throughput

0.650

High

843194

TCPD
T-complex protein 1 subunit delta

3

20

High-throughput

0.650

High

1046403

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

1046408

EFHC2
EF-hand domain-containing family member C2

4

1

High-throughput

0.637

High

431838

HS90A
Heat shock protein HSP 90-alpha

3

20

High-throughput

0.633

High

438160

HS90B
Heat shock protein HSP 90-beta

3

20

High-throughput

0.633

High

147156

FCHO1
F-BAR domain only protein 1

2

7

High-throughput

0.628

High

1046410

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

2

20

High-throughput

0.628

High

147422

SOCS3
Suppressor of cytokine signaling 3

1

19

Small-scale

0.618

High

681838

AKT1
RAC-alpha serine/threonine-protein kinase

1

20

Small-scale

0.618

High

849890

STA5B
Signal transducer and activator of transcription 5B

1

12

Small-scale

0.618

High

941901

PITX1
Pituitary homeobox 1

2

7

High-throughput

0.606

High

1027603

CBLB
E3 ubiquitin-protein ligase CBL-B

2

20

High-throughput

0.606

High

1046409

SKT
Sickle tail protein homolog

2

8

High-throughput

0.606

High

1046413

DTX3
Probable E3 ubiquitin-protein ligase DTX3

2

7

High-throughput

0.606

High

1046420

ZN341
Zinc finger protein 341

2

3

High-throughput

0.606

High

1046421

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

2

High-throughput

0.606

High

791548

HD
Huntingtin

2

4

High-throughput

0.596

High

1046404

CDC37
Hsp90 co-chaperone Cdc37

2

14

High-throughput

0.594

High

154485

MEIS2
Homeobox protein Meis2

2

0

High-throughput

0.580

High

126933

WASL
Actin nucleation-promoting factor WASL

1

20

High-throughput

0.573

High

981572

REL
Proto-oncogene c-Rel

1

4

High-throughput

0.573

High

202159

HNRPR
Heterogeneous nuclear ribonucleoprotein R

2

5

High-throughput

0.571

High

241306

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

2

12

High-throughput

0.571

High

243401

DNJA2
DnaJ homolog subfamily A member 2

2

5

High-throughput

0.571

High

272130

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

2

7

High-throughput

0.571

High

388428

HSPB1
Heat shock protein beta-1

2

7

High-throughput

0.571

High

428198

TBB5
Tubulin beta chain

2

7

High-throughput

0.571

High

432701

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

2

13

High-throughput

0.571

High

498275

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

7

High-throughput

0.571

High

499743

CH60
60 kDa heat shock protein, mitochondrial

2

7

High-throughput

0.571

High

502083

BIP
Endoplasmic reticulum chaperone BiP

2

20

High-throughput

0.571

High

504053

HSP7C
Heat shock cognate 71 kDa protein

2

13

High-throughput

0.571

High

564074

HSP76
Heat shock 70 kDa protein 6

2

13

High-throughput

0.571

High

571448

DDX5
Probable ATP-dependent RNA helicase DDX5

2

2

High-throughput

0.571

High

623118

EF1B
Elongation factor 1-beta

2

1

High-throughput

0.571

High

678619

METK2
S-adenosylmethionine synthase isoform type-2

2

2

High-throughput

0.571

High

681442

DNJA1
DnaJ homolog subfamily A member 1

2

5

High-throughput

0.571

High

751622

GRP75
Stress-70 protein, mitochondrial

2

20

High-throughput

0.571

High

770827

TCPZ
T-complex protein 1 subunit zeta

2

20

High-throughput

0.571

High

821206

TCPE
T-complex protein 1 subunit epsilon

2

20

High-throughput

0.571

High

852918

HNRPM
Heterogeneous nuclear ribonucleoprotein M

2

4

High-throughput

0.571

High

858253

TXTP
Tricarboxylate transport protein, mitochondrial

2

7

High-throughput

0.571

High

933201

TBA1B
Tubulin alpha-1B chain

2

11

High-throughput

0.571

High

933439

TBA4A
Tubulin alpha-4A chain

2

11

High-throughput

0.571

High

933801

TBB4B
Tubulin beta-4B chain

2

7

High-throughput

0.571

High

943224

TCPB
T-complex protein 1 subunit beta

2

20

High-throughput

0.571

High

1046411

YTHD3
YTH domain-containing family protein 3

2

4

High-throughput

0.571

High

1046418

TCPH
T-complex protein 1 subunit eta

2

20

High-throughput

0.571

High

1046422

ATD3A
ATPase family AAA domain-containing protein 3A

2

2

High-throughput

0.571

High

1046423

TECR
Very-long-chain enoyl-CoA reductase

2

2

High-throughput

0.571

High

1046426

YTHD2
YTH domain-containing family protein 2

2

4

High-throughput

0.571

High

1023459

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

2

1

High-throughput

0.553

High

613450

SFPQ
Splicing factor, proline- and glutamine-rich

1

7

Small-scale

0.546

High

487415

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

882730

STX17
Syntaxin-17

1

1

High-throughput

0.536

High

507989

FGFR1
Fibroblast growth factor receptor 1

1

20

Small-scale

0.527

High

1046417

DOK1
Docking protein 1

1

20

Small-scale

0.527

High

1046424

STAP2
Signal-transducing adaptor protein 2

1

4

Small-scale

0.527

High

159481

QCR8
Cytochrome b-c1 complex subunit 8

2

1

High-throughput

0.521

High

314986

SGPL1
Sphingosine-1-phosphate lyase 1

2

5

High-throughput

0.521

High

1034749

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

20

Small-scale

0.515

High

1046425

IKZF3
Zinc finger protein Aiolos

1

7

High-throughput

0.515

High

394692

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.501

High

1046405

HIF1A
Hypoxia-inducible factor 1-alpha

1

7

Small-scale

0.501

High

303683

OR2A4
Olfactory receptor 2A4

1

1

High-throughput

0.489

High

608900

SPR2E
Small proline-rich protein 2E

1

3

High-throughput

0.479

High

608917

SPR2D
Small proline-rich protein 2D

1

2

High-throughput

0.479

High

722882

SPR2B
Small proline-rich protein 2B

1

8

High-throughput

0.479

High

722889

SPR2A
Small proline-rich protein 2A

1

6

High-throughput

0.479

High

1046401

RBM39
RNA-binding protein 39

1

9

High-throughput

0.479

High

1046416

SPR2F
Small proline-rich protein 2F

1

1

High-throughput

0.479

High

1046402

GPNMB
Transmembrane glycoprotein NMB

1

0

Small-scale

0.458

High

1046419

SPR2G
Small proline-rich protein 2G

1

0

High-throughput

0.458

High

1046407

H90B3
Putative heat shock protein HSP 90-beta-3

1

20

High-throughput

0.445

High

1046414

MYOZ3
Myozenin-3

2

0

High-throughput

0.316

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024