Interactor 1: Q7K126 (Q7K126)
CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3)
Gene: Not3

Interactor 2: RGA (Q94547)
Regulator of gene activity (Protein regena) (CCR4-NOT transcription complex subunit 2 homolog) (CNOT2) (Not2)
Gene: RGA

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 23303381, 25242320, 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NOT2_3_5_C~NOT2_3_5_C
Common GO terms GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0005634 - nucleus
GO:0005829 - cytosol
and 6 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 844
Dm

1 585
+ Hs
+ Mm
+ Ce
+ Ce
+ Sc
+ Ce
+ Ce
+ Sc
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025