Interactor 1: Q7K3W2 (Q7K3W2)
Mitochondrial-processing peptidase subunit alpha (Alpha-MPP) (Inactive zinc metalloprotease alpha)
Gene: DmelCG8728

Interactor 2: Q9VFF0 (Q9VFF0)
Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP)
Gene: UQCR-C1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_M16~Peptidase_M16, Peptidase_M16~Peptidase_M16_C, Peptidase_M16_C~Peptidase_M16_C
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006627 - protein processing involved in protein targeting to mitochondrion
GO:0017087 - mitochondrial processing peptidase complex
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 556
Dm

1 470
+ Hs
+ Mm
+ Hs
+ Ce
+ Mm
+ Hs
+ Hs
+ Sc
+ Mm
+ Dm
+ Sc
+ Hs
+ Sc

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Last updated: 11Aug2025