Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: WIPF1 (O43516)
WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 25416956, 11331876, 28514442, 23414517, 33961781, 12372256, 35271311, 16582881
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, two hybrid fragment pooling approach, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains WH2~WH2
Common GO terms GO:0003779 - actin binding
GO:0005829 - cytosol
GO:0008154 - actin polymerization or depolymerization
GO:0015629 - actin cytoskeleton
GO:0031410 - cytoplasmic vesicle
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 505
Hs

1 503
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Last updated: 15 Jul 2024