HitPredict

Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: VINEX (O60504)
Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)
Gene: SORBS3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	18662323, 16483316
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 671
+	Hs
		203191 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		VINEX_HUMAN (1-671): 2.64e-132: 406: 100.00
+	Rn
		192744 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		SRBS2_RAT (56-671): 3.74e-63: 229: 27.36
+	Hs
		203192 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SRBS2_HUMAN (56-671): 2.3e-57: 212: 26.28
+	Hs
		298960 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		SRBS2_HUMAN (56-671): 2.3e-57: 212: 26.28
+	Dm
		112580 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		M9ND00_DROME (44-544): 9.5e-32: 134: 15.98
+	Dm
		1361426 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		Q9VIF7_DROME (44-520): 1.75e-30: 130: 16.56
+	Hs
		203250 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SRBS1_HUMAN (522-671): 2.49e-20: 98.4: 35.53
+	Hs
		203262 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		PACN2_HUMAN (433-671): 4.38e-18: 89.7: 15.98
+	Hs
		203228 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02
+	Hs
		166049 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02
+	Hs
		166056 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN2_HUMAN (116-671): 3.14e-15: 82: 10.46
+	Hs
		203241 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86
+	Hs
		203230 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SH319_HUMAN (39-671): 7.07e-13: 73.9: 10.88
+	Hs
		166055 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86
+	Hs
		166060 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		CD2AP_HUMAN (614-671): 8.75e-11: 67.2: 27.12
+	Hs
		790671 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89
+	Hs
		790694 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		PACN2_HUMAN (433-671): 4.38e-18: 89.7: 15.98
+	Hs
		790676 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02
+	Hs
		790688 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		ITSN2_HUMAN (116-671): 3.14e-15: 82: 10.46
+	Ce
		104723 Q8MQE6_CAEEL (164-455): 3.55e-41: 159: 27.17		SRBS1_CAEEL (182-671): 5.35e-11: 68.2: 11.88