HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: FOXJ2 (Q9P0K8)
Forkhead box protein J2 (Fork head homologous X)
Gene: FOXJ2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 488 Hs			1 574
+	Hs
		1270410 HDAC2_HUMAN (1-488): 0: 707: 100.00		FOXC2_HUMAN (21-362): 8.61e-48: 175: 22.63
+	Hs
		877628 HDAC2_HUMAN (1-488): 0: 707: 100.00		FOXG1_HUMAN (23-366): 1.74e-46: 172: 20.35
+	Hs
		964220 HDAC2_HUMAN (1-488): 0: 707: 100.00		FOXK2_HUMAN (1-437): 1.01e-45: 172: 17.61
+	Hs
		1021331 HDAC2_HUMAN (1-488): 0: 707: 100.00		FOXL1_HUMAN (60-230): 9.22e-46: 166: 33.72
+	Hs
		952845 HDAC2_HUMAN (1-488): 0: 707: 100.00		FOXK1_HUMAN (1-406): 6.81e-43: 165: 18.01
+	Hs
		208927 HDAC2_HUMAN (1-488): 0: 707: 100.00		FOXS1_HUMAN (50-313): 4.95e-44: 161: 24.91
+	Hs
		877999 HDAC2_HUMAN (1-488): 0: 707: 100.00		FOXA3_HUMAN (5-269): 7.29e-44: 161: 24.53
+	Hs
		964178 HDAC1_HUMAN (1-443): 0: 642: 90.07		FOXK2_HUMAN (1-437): 1.01e-45: 172: 17.61
+	Hs
		952807 HDAC1_HUMAN (1-443): 0: 642: 90.07		FOXK1_HUMAN (1-406): 6.81e-43: 165: 18.01
+	Hs
		1038595 HDAC1_HUMAN (1-443): 0: 642: 90.07		FOXJ1_HUMAN (13-282): 1.89e-42: 159: 27.11
+	Hs
		177261 HDAC3_HUMAN (10-431): 0: 574: 58.26		FOXK2_HUMAN (1-437): 1.01e-45: 172: 17.61
+	Hs
		177281 HDAC3_HUMAN (10-431): 0: 574: 58.26		FOXL1_HUMAN (60-230): 9.22e-46: 166: 33.72
+	Sp
		223482 CLR6_SCHPO (6-406): 0: 563: 60.89		FKH2_SCHPO (56-471): 1.28e-42: 164: 19.47
+	Mm
		1157849 HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89		FOXO1_MOUSE (15-455): 6.66e-39: 153: 19.96
+	Hs
		1021370 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		FOXL1_HUMAN (60-230): 9.22e-46: 166: 33.72
+	Hs
		877811 HDAC7_HUMAN (29-280): 1.96e-23: 106: 26.37		FOXA1_HUMAN (15-352): 6.28e-44: 164: 23.50