HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: CDYL (Q9Y232)
Chromodomain Y-like protein (CDY-like) (Crotonyl-CoA hydratase) (EC 4.2.1.-)
Gene: CDYL

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.745

Property	Details
Experiments	12947414, 19061646, 21258344, 30737378, 35271311, 23752268, 26949739
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 488 Hs			1 598
+	Hs
		1038833 HDAC1_HUMAN (1-443): 0: 642: 90.07		CDYL_HUMAN (1-598): 0: 600: 100.00
+	Hs
		778233 HDAC2_HUMAN (1-488): 0: 707: 100.00		ECHA_HUMAN (352-557): 5.41e-49: 183: 23.87
+	Hs
		800478 HDAC2_HUMAN (1-488): 0: 707: 100.00		CBX5_HUMAN (63-149): 4.85e-09: 58.2: 39.08
+	Mm
		1157838 HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89		AUHM_MOUSE (320-598): 2.33e-71: 233: 20.35
+	Hs
		778320 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		ECHA_HUMAN (352-557): 5.41e-49: 183: 23.87