Interactor 1: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Interactor 2: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 21157427, 12482983
Identification Methods enzymatic study, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Acetyltransf_1~Acetyltransf_1, Bromodomain~Bromodomain, PCAF_N~PCAF_N
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000123 - histone acetyltransferase complex
GO:0000124 - SAGA complex
GO:0001701 - in utero embryonic development
GO:0001756 - somitogenesis
and 62 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 837
Hs

1 837
+ Mm
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+ Hs
+ Mm
+ Hs
+ Mm
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+ Sc
+ Sc
+ Hs
+ Mm
+ Hs
+ Zm
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+ Hs
+ Hs

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Last updated: 15 Jul 2024