HitPredict

Interactor 1: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Interactor 2: DUS23 (Q9BVJ7)
Dual specificity protein phosphatase 23 (EC 3.1.3.16) (EC 3.1.3.48) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z)
Gene: DUSP23

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27432908
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1312 Hs			1 150
+	Hs
		1272066 RAD50_HUMAN (1-1312): 1.28e-115: 394: 100.00		DUS10_HUMAN (3-149): 5.04e-43: 149: 16.89
+	Hs
		1116768 RAD50_HUMAN (1-1312): 1.28e-115: 394: 100.00		DUS28_HUMAN (11-150): 3.87e-42: 139: 19.15
+	Sc
		521151 RAD50_YEAST (1-1305): 6.58e-67: 250: 25.15		CDC14_YEAST (3-144): 1.3e-45: 157: 21.61
+	Sc
		961523 SMC4_YEAST (3-1285): 1.44e-50: 198: 10.82		CDC14_YEAST (3-144): 1.3e-45: 157: 21.61
+	Hs
		724891 MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19		SSH2_HUMAN (9-146): 3.91e-43: 153: 16.55
+	Hs
		1113841 GRDN_HUMAN (530-1217): 5.01e-21: 102: 12.32		DUS16_HUMAN (4-150): 3.82e-46: 160: 18.92
+	Hs
		985175 SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17		DUS2_HUMAN (10-149): 5.48e-47: 156: 17.02
+	Hs
		1176213 MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45		SSH2_HUMAN (9-146): 3.91e-43: 153: 16.55
+	Hs
		1057427 SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17		CC14A_HUMAN (3-144): 8.97e-42: 147: 25.64
+	Hs
		725210 MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20		SSH1_HUMAN (10-146): 5.72e-43: 152: 15.22
+	Hs
		260524 MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19		TP4A3_HUMAN (31-145): 1.25e-34: 120: 26.27
+	Hs
		1057377 SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17		DUS26_HUMAN (12-150): 4.58e-42: 140: 19.44
+	Hs
		551612 DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71		DUS1_HUMAN (10-149): 1.21e-50: 166: 17.02
+	Hs
		551686 DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71		DUS4_HUMAN (10-149): 8.49e-49: 163: 17.02
+	Hs
		148975 CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15		SSH2_HUMAN (9-146): 3.91e-43: 153: 16.55
+	Hs
		890777 MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45		PTEN_HUMAN (14-145): 4.82e-20: 86.6: 20.57
+	Hs
		1057333 SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17		PTPM1_HUMAN (12-148): 8.76e-21: 85.5: 21.92
+	Hs
		725123 MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20		PTEN_HUMAN (14-145): 4.82e-20: 86.6: 20.57
+	Mm
		139340 CTRO_MOUSE (183-685): 1.18e-10: 68.8: 13.48		PTEN_MOUSE (14-145): 4.72e-20: 86.6: 20.57
+	Hs
		551649 DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71		PTEN_HUMAN (14-145): 4.82e-20: 86.6: 20.57