HitPredict

Interactor 1: TR10A (O00220)
Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261)
Gene: TNFRSF10A

Interactor 2: AVR2A (P27037)
Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)
Gene: ACVR2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 468 Hs			1 513
+	Hs
		127643 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		BMR1A_HUMAN (59-488): 2.94e-128: 385: 33.41
+	Hs
		127644 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		TGFR2_HUMAN (28-493): 8.85e-123: 372: 33.79
+	Hs
		127669 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		ACVR1_HUMAN (47-493): 6.74e-117: 355: 30.27
+	Hs
		163301 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		AVR2B_HUMAN (4-513): 3.69e-142: 420: 67.12
+	Hs
		163250 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		BMR1A_HUMAN (59-488): 2.94e-128: 385: 33.41
+	Hs
		163252 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		TGFR2_HUMAN (28-493): 8.85e-123: 372: 33.79
+	Hs
		163286 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		ACVR1_HUMAN (47-493): 6.74e-117: 355: 30.27
+	Hs
		690133 TR10D_HUMAN (60-367): 5.79e-64: 213: 46.94		AVR2A_HUMAN (1-513): 3.38e-154: 451: 100.00