HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	35031058, 29395067, 36232890, 23125841
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 579 Hs			1 577
+	Hs
		323234 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		STAU1_HUMAN (1-577): 0: 524: 100.00
+	Mm
		291676 IF2B1_MOUSE (1-577): 5.34e-136: 409: 71.06		STAU1_MOUSE (89-577): 5.34e-156: 457: 91.00
+	Hs
		322666 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		STAU1_HUMAN (1-577): 0: 524: 100.00
+	Hs
		322977 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		STAU1_HUMAN (1-577): 0: 524: 100.00
+	Hs
		322667 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		STAU1_HUMAN (1-577): 0: 524: 100.00
+	Hs
		1302237 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33
+	Hs
		323382 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		STAU1_HUMAN (1-577): 0: 524: 100.00
+	Hs
		269921 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42
+	Hs
		128158 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		ILF3_HUMAN (245-488): 2.36e-15: 81.6: 15.45
+	Hs
		128022 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		E2AK2_HUMAN (98-258): 1.74e-11: 68.9: 22.67
+	Hs
		1346003 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		STAU2_HUMAN (177-569): 4.96e-21: 99: 16.46
+	Hs
		1019981 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		ILF3_HUMAN (245-488): 2.36e-15: 81.6: 15.45
+	Xl
		251134 IF23A_XENLA (1-579): 1.82e-136: 411: 77.44		Q5MNU4_XENLA (113-554): 2.36e-13: 75.1: 15.45
+	Hs
		944795 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		RED1_HUMAN (254-488): 1.1e-31: 132: 17.92
+	Hs
		269741 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42
+	Hs
		269828 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42
+	Hs
		1019757 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		ILF3_HUMAN (245-488): 2.36e-15: 81.6: 15.45
+	Mm
		956556 PCBP2_MOUSE (193-484): 2.7e-30: 123: 21.16		TRBP2_MOUSE (87-352): 3.06e-17: 85.5: 17.11
+	Hs
		585480 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		E2AK2_HUMAN (98-258): 1.74e-11: 68.9: 22.67
+	Hs
		585598 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		E2AK2_HUMAN (98-258): 1.74e-11: 68.9: 22.67