HitPredict

Interactor 1: YIPF5 (Q969M3)
Protein YIPF5 (Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5) (Smooth muscle cell-associated protein 5) (SMAP-5) (YIP1 family member 5) (YPT-interacting protein 1 A)
Gene: YIPF5

Interactor 2: RAB18 (Q9NP72)
Ras-related protein Rab-18
Gene: RAB18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005794 - Golgi apparatus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 257 Hs			1 206
+	Hs
		918926 YIPF5_HUMAN (1-257): 7.63e-114: 328: 100.00		RAB1A_HUMAN (1-200): 1.22e-82: 245: 43.84
+	Hs
		1281690 YIPF5_HUMAN (1-257): 7.63e-114: 328: 100.00		RAB1B_HUMAN (1-200): 8.72e-82: 243: 42.57
+	Hs
		895219 YIPF5_HUMAN (1-257): 7.63e-114: 328: 100.00		RAB2A_HUMAN (9-187): 5.36e-55: 175: 50.00
+	Hs
		1259986 YIPF5_HUMAN (1-257): 7.63e-114: 328: 100.00		RAB2B_HUMAN (9-191): 3.72e-54: 173: 48.40
+	Dm
		185500 Q9VK46_DROME (1-257): 1.14e-78: 239: 47.06		O18332_DROME (2-199): 2.61e-78: 234: 41.58
+	Sc
		350898 YIP1_YEAST (11-257): 1.27e-51: 170: 32.43		YPT1_YEAST (1-199): 1.87e-83: 247: 42.03
+	Sc
		350899 YIP4_YEAST (43-255): 9.27e-51: 167: 18.33		YPT1_YEAST (1-199): 1.87e-83: 247: 42.03