HitPredict

Interactor 1: SPSB4 (Q96A44)
SPRY domain-containing SOCS box protein 4 (SSB-4)
Gene: SPSB4

Interactor 2: PCD16 (Q96JQ0)
Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1)
Gene: DCHS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 273 Hs			1 3298
+	Hs
		1171266 TRI67_HUMAN (52-232): 1.14e-36: 139: 19.37		PCD16_HUMAN (1-3298): 0: 3079: 99.61
+	Hs
		1255521 SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00		FAT3_HUMAN (2-2697): 0: 1770: 25.09
+	Hs
		1055003 SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00		FAT1_HUMAN (1323-2954): 0: 997: 23.52
+	Hs
		1167031 SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00		FAT4_HUMAN (2-1318): 0: 937: 26.14
+	Hs
		472707 FBSP1_HUMAN (36-230): 2.9e-71: 222: 41.33		FAT4_HUMAN (2-1318): 0: 937: 26.14
+	Hs
		1283469 SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00		CELR1_HUMAN (2-884): 0: 724: 27.45
+	Hs
		1140545 RN123_HUMAN (87-239): 2.19e-33: 130: 21.38		FAT4_HUMAN (2-1318): 0: 937: 26.14
+	Hs
		1283470 SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00		CELR3_HUMAN (2-781): 0: 656: 27.55
+	Hs
		1172016 TRI67_HUMAN (52-232): 1.14e-36: 139: 19.37		CELR1_HUMAN (2-884): 0: 724: 27.45
+	Hs
		1283464 SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00		CELR2_HUMAN (1-462): 1.2e-92: 340: 25.11
+	Hs
		1305209 SPSB2_HUMAN (1-273): 8.89e-98: 289: 50.92		CELR2_HUMAN (1-462): 1.2e-92: 340: 25.11
+	Hs
		1250855 SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00		PCD19_HUMAN (2468-2869): 1.32e-36: 154: 30.90
+	Hs
		225662 SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00		PCDH7_HUMAN (963-1548): 9.52e-34: 145: 27.04
+	Hs
		158335 SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00		PCD17_HUMAN (1852-2471): 1.94e-31: 138: 26.98
+	Hs
		1172441 TRI67_HUMAN (52-232): 1.14e-36: 139: 19.37		PCDGI_HUMAN (2-464): 2.81e-97: 340: 26.21
+	Hs
		993897 SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00		PCDH1_HUMAN (53-359): 1.94e-20: 102: 29.65
+	Hs
		993902 SPSB2_HUMAN (1-273): 8.89e-98: 289: 50.92		PCDH1_HUMAN (53-359): 1.94e-20: 102: 29.65
+	Hs
		158328 TRI67_HUMAN (52-232): 1.14e-36: 139: 19.37		PCD17_HUMAN (1852-2471): 1.94e-31: 138: 26.98
+	Hs
		158327 RN123_HUMAN (87-239): 2.19e-33: 130: 21.38		PCD17_HUMAN (1852-2471): 1.94e-31: 138: 26.98
+	Hs
		1140873 RN123_HUMAN (87-239): 2.19e-33: 130: 21.38		PCDBF_HUMAN (568-1054): 2.09e-27: 124: 27.05