Interactor 1: DHX58 (Q96C10)
ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (ATP-dependent helicase LGP2) (Protein D11Lgp2 homolog) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor LGP2) (RLR)
Gene: DHX58

Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 21903422
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~Helicase_C, Helicase_C~ResIII, ResIII~ResIII, Helicase_C~RIG-I_C, RIG-I_C~ResIII, Helicase_C~RIG-I_C-RD, RIG-I_C-RD~ResIII
Common GO terms GO:0003677 - DNA binding
GO:0003725 - double-stranded RNA binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 678
Hs

1 1922
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ At
+ At
+ Hs
+ Ce
+ Ce
+ Hs
+ At
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024