HitPredict

Interactor 1: FAF2 (Q96CS3)
FAS-associated factor 2 (UBX domain-containing protein 3B) (UBX domain-containing protein 8)
Gene: FAF2

Interactor 2: RN126 (Q9BV68)
E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126)
Gene: RNF126

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	18775313
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 445 Hs			1 311
+	Hs
		196335 FAF2_HUMAN (1-445): 1.33e-143: 419: 100.00		PJA2_HUMAN (2-303): 4.11e-46: 167: 16.88
+	Hs
		1245286 FAF2_HUMAN (1-445): 1.33e-143: 419: 100.00		PJA1_HUMAN (38-276): 2.32e-29: 119: 20.33
+	Hs
		1204809 FAF2_HUMAN (1-445): 1.33e-143: 419: 100.00		GOLI_HUMAN (205-311): 1.76e-29: 118: 29.57
+	Hs
		1313516 FAF1_HUMAN (112-440): 5.62e-83: 269: 24.79		RN126_HUMAN (1-311): 3.19e-81: 250: 100.00
+	Hs
		196248 UBXN7_HUMAN (1-441): 1.1e-116: 352: 16.34		PJA2_HUMAN (2-303): 4.11e-46: 167: 16.88
+	Hs
		299400 UBXN7_HUMAN (1-441): 1.1e-116: 352: 16.34		ARK2C_HUMAN (67-281): 1.9e-31: 122: 19.48
+	Hs
		196370 FAF1_HUMAN (112-440): 5.62e-83: 269: 24.79		PJA2_HUMAN (2-303): 4.11e-46: 167: 16.88
+	Hs
		979349 UBXN1_HUMAN (295-439): 7.93e-19: 88.4: 16.36		RN126_HUMAN (1-311): 3.19e-81: 250: 100.00
+	Hs
		196296 UBXN1_HUMAN (295-439): 7.93e-19: 88.4: 16.36		PJA2_HUMAN (2-303): 4.11e-46: 167: 16.88
+	Hs
		1204802 UBXN4_HUMAN (268-442): 1.92e-23: 104: 17.05		GOLI_HUMAN (205-311): 1.76e-29: 118: 29.57