HitPredict

Interactor 1: RETR3 (Q86VR2)
Reticulophagy regulator 3
Gene: RETREG3

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.50	0.660

Property	Details
Experiments	29892012, 25416956, 32296183, 26040720, unassigned1304
Identification Methods	two hybrid, pull down, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 117
+	Hs
		952230 RETR3_HUMAN (1-466): 0: 726: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		328060 RETR3_HUMAN (1-466): 0: 726: 100.00		GBRAP_HUMAN (1-116): 2.97e-56: 171: 87.07
+	Hs
		1291495 RETR3_HUMAN (1-466): 0: 726: 100.00		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Hs
		1291486 RETR3_HUMAN (1-466): 0: 726: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		952346 RETR1_HUMAN (42-459): 0: 584: 36.82		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1430328 RETR1_HUMAN (42-459): 0: 584: 36.82		GBRL1_HUMAN (1-117): 4.56e-56: 171: 100.00
+	Hs
		328157 RETR1_HUMAN (42-459): 0: 584: 36.82		GBRAP_HUMAN (1-116): 2.97e-56: 171: 87.07
+	Mm
		1354022 RETR1_MOUSE (8-459): 0: 600: 36.23		MLP3B_MOUSE (2-116): 3.04e-44: 141: 31.62
+	Hs
		1433196 RETR1_HUMAN (42-459): 0: 584: 36.82		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Hs
		1428354 RETR1_HUMAN (42-459): 0: 584: 36.82		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		64580 RETR1_HUMAN (42-459): 0: 584: 36.82		MP3B2_HUMAN (2-116): 6.74e-43: 138: 30.77
+	Hs
		1334649 RETR2_HUMAN (46-459): 1.24e-172: 497: 34.14		GBRL1_HUMAN (1-117): 4.56e-56: 171: 100.00
+	Hs
		328071 RETR2_HUMAN (46-459): 1.24e-172: 497: 34.14		GBRAP_HUMAN (1-116): 2.97e-56: 171: 87.07
+	Hs
		1334650 RETR2_HUMAN (46-459): 1.24e-172: 497: 34.14		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Hs
		1334648 RETR2_HUMAN (46-459): 1.24e-172: 497: 34.14		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62