HitPredict

Interactor 1: MLP3A (Q9H492)
Microtubule-associated protein 1 light chain 3 alpha (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (Microtubule-associated proteins 1A/1B light chain 3A) (MAP1A/MAP1B LC3 A) (MAP1A/MAP1B light chain 3 A)
Gene: MAP1LC3A

Interactor 2: RETR1 (Q9H6L5)
Reticulophagy regulator 1 (Reticulophagy receptor 1)
Gene: RETREG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	31006538, 36952345, 26040720
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000423 - mitophagy
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 121 Hs			1 497
+	Mm
		1354022 MLP3B_MOUSE (1-120): 3.17e-52: 162: 82.50		RETR1_MOUSE (1-497): 0: 767: 87.32
+	Hs
		952346 GBRL2_HUMAN (7-121): 5.56e-54: 166: 41.74		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1428354 MLP3B_HUMAN (1-121): 6.68e-52: 161: 81.82		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		328157 GBRAP_HUMAN (7-121): 3.01e-52: 161: 30.44		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		64580 MP3B2_HUMAN (1-121): 4.08e-51: 159: 80.99		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1430328 GBRL1_HUMAN (3-120): 5.99e-51: 158: 33.05		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1291495 MLP3A_HUMAN (1-121): 4.21e-54: 167: 100.00		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		952230 GBRL2_HUMAN (7-121): 5.56e-54: 166: 41.74		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1291486 MLP3B_HUMAN (1-121): 6.68e-52: 161: 81.82		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		328060 GBRAP_HUMAN (7-121): 3.01e-52: 161: 30.44		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1291489 GBRL1_HUMAN (3-120): 5.99e-51: 158: 33.05		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1334650 MLP3A_HUMAN (1-121): 4.21e-54: 167: 100.00		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57
+	Hs
		1334648 MLP3B_HUMAN (1-121): 6.68e-52: 161: 81.82		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57
+	Hs
		328071 GBRAP_HUMAN (7-121): 3.01e-52: 161: 30.44		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57
+	Hs
		1334649 GBRL1_HUMAN (3-120): 5.99e-51: 158: 33.05		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57