HitPredict

Interactor 1: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Interactor 2: RETR1 (Q9H6L5)
Reticulophagy regulator 1 (Reticulophagy receptor 1)
Gene: RETREG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.708

Property	Details
Experiments	29867141, 31006538, 32620754, 37225996, 26040720
Identification Methods	pull down, affinity chromatography technology, unspecified method, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000423 - mitophagy
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 497
+	Hs
		952346 GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1430328 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Mm
		1354022 MLP3B_MOUSE (2-116): 2.1e-44: 142: 30.77		RETR1_MOUSE (1-497): 0: 767: 87.32
+	Hs
		1433196 MLP3A_HUMAN (5-117): 2.3e-45: 144: 30.44		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1428354 MLP3B_HUMAN (2-117): 3.56e-44: 141: 30.51		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		64580 MP3B2_HUMAN (2-117): 2.37e-43: 139: 29.66		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		952230 GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		328060 GBRAP_HUMAN (1-117): 8.09e-57: 173: 100.00		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1291489 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1291495 MLP3A_HUMAN (5-117): 2.3e-45: 144: 30.44		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1291486 MLP3B_HUMAN (2-117): 3.56e-44: 141: 30.51		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		328071 GBRAP_HUMAN (1-117): 8.09e-57: 173: 100.00		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57
+	Hs
		1334649 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57
+	Hs
		1334650 MLP3A_HUMAN (5-117): 2.3e-45: 144: 30.44		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57
+	Hs
		1334648 MLP3B_HUMAN (2-117): 3.56e-44: 141: 30.51		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57