HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: RETR1 (Q9H6L5)
Reticulophagy regulator 1 (Reticulophagy receptor 1)
Gene: RETREG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.658

Property	Details
Experiments	32296183, 26040720, unassigned1304
Identification Methods	two hybrid, pull down, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000423 - mitophagy GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 497
+	Hs
		328157 GBRAP_HUMAN (1-117): 7.58e-57: 173: 57.27		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1430328 GBRL1_HUMAN (1-116): 7.93e-56: 170: 61.21		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Mm
		1354022 MLP3B_MOUSE (2-116): 2.54e-44: 141: 38.46		RETR1_MOUSE (1-497): 0: 767: 87.32
+	Hs
		1433196 MLP3A_HUMAN (5-117): 2.02e-45: 144: 41.74		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1428354 MLP3B_HUMAN (2-117): 6.37e-44: 141: 38.14		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		64580 MP3B2_HUMAN (2-117): 4e-43: 139: 37.29		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		952230 GBRL2_HUMAN (1-117): 1.09e-58: 178: 100.00		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		328060 GBRAP_HUMAN (1-117): 7.58e-57: 173: 57.27		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1291489 GBRL1_HUMAN (1-116): 7.93e-56: 170: 61.21		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1291495 MLP3A_HUMAN (5-117): 2.02e-45: 144: 41.74		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1291486 MLP3B_HUMAN (2-117): 6.37e-44: 141: 38.14		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		328071 GBRAP_HUMAN (1-117): 7.58e-57: 173: 57.27		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57
+	Hs
		1334649 GBRL1_HUMAN (1-116): 7.93e-56: 170: 61.21		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57
+	Hs
		1334650 MLP3A_HUMAN (5-117): 2.02e-45: 144: 41.74		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57
+	Hs
		1334648 MLP3B_HUMAN (2-117): 6.37e-44: 141: 38.14		RETR2_HUMAN (77-472): 2.57e-164: 477: 28.57