HitPredict

Interactor 1: RETR3 (Q86VR2)
Reticulophagy regulator 3
Gene: RETREG3

Interactor 2: REEP4 (Q9H6H4)
Receptor expression-enhancing protein 4
Gene: REEP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	33961781, 37225996, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0071782 - endoplasmic reticulum tubular network GO:0071786 - endoplasmic reticulum tubular network organization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 257
+	Hs
		1238308 RETR3_HUMAN (1-466): 0: 726: 100.00		REEP3_HUMAN (1-249): 3.54e-88: 263: 53.10
+	Hs
		1291458 RETR3_HUMAN (1-466): 0: 726: 100.00		REEP6_HUMAN (1-181): 2.43e-61: 193: 25.28
+	Hs
		1027063 RETR3_HUMAN (1-466): 0: 726: 100.00		REEP5_HUMAN (1-125): 1.01e-59: 188: 35.71
+	Hs
		1434941 RETR1_HUMAN (42-459): 0: 584: 36.82		REEP4_HUMAN (1-257): 1.85e-108: 315: 100.00
+	Hs
		1411240 RETR1_HUMAN (42-459): 0: 584: 36.82		REEP2_HUMAN (1-257): 5.22e-84: 253: 52.69
+	Hs
		1027183 RETR1_HUMAN (42-459): 0: 584: 36.82		REEP5_HUMAN (1-125): 1.01e-59: 188: 35.71
+	Hs
		1027090 RETR2_HUMAN (46-459): 1.24e-172: 497: 34.14		REEP5_HUMAN (1-125): 1.01e-59: 188: 35.71