HitPredict

Interactor 1: Q8AW91 (Q8AW91)
Structural maintenance of chromosomes protein
Gene: smc3.L

Interactor 2: STAG2 (Q9DGN0)
Cohesin subunit SA-2 (xSA-2) (SCC3 homolog 2) (Stromal antigen 2 homolog)
Gene: STAG2

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	10931856, 15855230
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1217 Xl			1 1194
+	Xl
		1220148 Q8AW91_XENLA (1-1217): 1.34e-126: 421: 100.00		Q5XGV2_XENLA (1-1194): 0: 1644: 97.82
+	Xl
		313489 SMC3_XENLA (1-1217): 7.81e-124: 413: 99.01		STAG2_XENLA (1-1194): 0: 1634: 100.00
+	Mm
		205301 SMC3_MOUSE (1-1217): 1.85e-124: 415: 96.80		STAG2_MOUSE (1-1194): 0: 1574: 88.50
+	Hs
		1325410 SMC3_HUMAN (1-1217): 3.22e-124: 414: 96.71		STAG2_HUMAN (1-1194): 0: 1572: 88.42
+	Hs
		1358313 SMC3_HUMAN (1-1217): 3.22e-124: 414: 96.71		STAG1_HUMAN (2-1194): 0: 1553: 71.19
+	Xl
		313490 SMC3_XENLA (1-1217): 7.81e-124: 413: 99.01		STAG1_XENLA (2-1194): 0: 1526: 70.39
+	Xl
		313480 SMC1A_XENLA (2-1211): 1.19e-76: 279: 15.79		Q5XGV2_XENLA (1-1194): 0: 1644: 97.82
+	Xl
		313482 SMC1A_XENLA (2-1211): 1.19e-76: 279: 15.79		STAG2_XENLA (1-1194): 0: 1634: 100.00
+	Mm
		205300 SMC1A_MOUSE (2-1211): 4.37e-82: 295: 15.75		STAG2_MOUSE (1-1194): 0: 1574: 88.50
+	Hs
		1130102 SMC1A_HUMAN (2-1211): 6.78e-82: 295: 15.75		STAG2_HUMAN (1-1194): 0: 1572: 88.42
+	Hs
		1130125 SMC1A_HUMAN (2-1211): 6.78e-82: 295: 15.75		STAG1_HUMAN (2-1194): 0: 1553: 71.19
+	Xl
		313483 SMC1A_XENLA (2-1211): 1.19e-76: 279: 15.79		STAG1_XENLA (2-1194): 0: 1526: 70.39
+	Hs
		1460564 SMC3_HUMAN (1-1217): 3.22e-124: 414: 96.71		STAG3_HUMAN (4-1094): 0: 1298: 51.41
+	Mm
		267237 SMC3_MOUSE (1-1217): 1.85e-124: 415: 96.80		STAG3_MOUSE (2-1094): 0: 1213: 50.32
+	Hs
		1130213 SMC1A_HUMAN (2-1211): 6.78e-82: 295: 15.75		STAG3_HUMAN (4-1094): 0: 1298: 51.41
+	Sp
		151730 SMC3_SCHPO (1-1212): 4.48e-87: 310: 39.19		SCC3_SCHPO (8-674): 0: 593: 21.56
+	Sp
		151732 SMC1_SCHPO (2-1204): 1.36e-68: 254: 15.58		SCC3_SCHPO (8-674): 0: 593: 21.56
+	Sp
		205973 SMC3_SCHPO (1-1212): 4.48e-87: 310: 39.19		REC11_SCHPO (12-639): 2.79e-150: 476: 15.58
+	Sp
		314035 SMC1_SCHPO (2-1204): 1.36e-68: 254: 15.58		REC11_SCHPO (12-639): 2.79e-150: 476: 15.58
+	Sc
		826162 SMC3_YEAST (1-1217): 5.57e-85: 304: 29.80		SCC3_YEAST (8-350): 7.13e-79: 284: 25.00