Interactor 1: ECHA (Q8BMS1)
Trifunctional enzyme subunit alpha, mitochondrial (Monolysocardiolipin acyltransferase) (MLCL AT) (EC 2.3.1.-) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]
Gene: Hadha

Interactor 2: ECHA (Q8BMS1)
Trifunctional enzyme subunit alpha, mitochondrial (Monolysocardiolipin acyltransferase) (MLCL AT) (EC 2.3.1.-) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]
Gene: Hadha

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 3HCDH~3HCDH, 3HCDH~3HCDH_N, 3HCDH~ECH_1, 3HCDH_N~3HCDH_N, 3HCDH_N~ECH_1, ECH_1~ECH_1
Common GO terms GO:0004300 - enoyl-CoA hydratase activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006635 - fatty acid beta-oxidation
GO:0016507 - mitochondrial fatty acid beta-oxidation multienzyme complex
and 7 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 763
Mm

1 763
+ Hs
+ Mm
+ Rn
+ Hs
+ Zm
+ Mm
+ Hs
+ Ce
+ Mt
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025