Interactor 1: HIBCH (Q6NVY1)
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)
Gene: HIBCH

Interactor 2: HIBCH (Q6NVY1)
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)
Gene: HIBCH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ECH_2~ECH_2
Common GO terms GO:0003860 - 3-hydroxyisobutyryl-CoA hydrolase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006574 - L-valine catabolic process
GO:0009083 - branched-chain amino acid catabolic process
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 386
Hs

1 386
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm
+ Dm
+ Ec

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Last updated: 11Aug2025