HitPredict

Interactor 1: SPAST (Q8I0P1)
Spastin (EC 5.6.1.1) (D-Spastin) (Dm-Spastin) (Dspastin)
Gene: spas

Interactor 2: Q9VRY6 (Q9VRY6)
IST1 homolog (Charged multivesicular body protein 8)
Gene: Ist1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.50	0.513

Property	Details
Experiments	14605208, 38944040
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Dm			1 417
+	Dm
		122089 SPAST_DROME (1-758): 1.58e-174: 521: 100.00		M9PHL4_DROME (1-417): 2.61e-122: 361: 92.09
+	Dm
		1485267 Q9Y162_DROME (460-755): 3.39e-119: 367: 39.52		Q9VRY6_DROME (1-417): 5.42e-131: 385: 100.00
+	Dm
		122113 Q9Y162_DROME (460-755): 3.39e-119: 367: 39.52		M9PHL4_DROME (1-417): 2.61e-122: 361: 92.09
+	Hs
		925689 SPAST_HUMAN (111-758): 3.65e-120: 375: 43.94		IST1_HUMAN (1-416): 4.26e-96: 294: 41.73
+	Hs
		925695 VPS4A_HUMAN (424-757): 8.25e-120: 368: 34.41		IST1_HUMAN (1-416): 4.26e-96: 294: 41.73
+	Ce
		112136 Q9BL83_CAEEL (473-706): 5.64e-64: 221: 51.06		G5EDV6_CAEEL (2-417): 2.04e-109: 330: 38.89
+	Ce
		111205 Q9BL83_CAEEL (473-706): 5.64e-64: 221: 51.06		G5ECX8_CAEEL (2-417): 4.75e-106: 322: 37.75
+	Sc
		915377 VPS4_YEAST (463-706): 6.15e-62: 216: 47.95		IST1_YEAST (6-178): 2.05e-58: 194: 31.49