HitPredict

Interactor 1: RB40C (Q96S21)
Ras-related protein Rab-40C (Rar-like protein) (Ras-like protein family member 8C) (SOCS box-containing protein RAR3)
Gene: RAB40C

Interactor 2: RBX2 (Q9UBF6)
RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)
Gene: RNF7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	33961781, 35512830, 15601820
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 281 Hs			1 113
+	Hs
		921402 RB40C_HUMAN (1-281): 8.84e-97: 287: 100.00		RBX1_HUMAN (18-112): 5.7e-38: 125: 46.94
+	Hs
		1017283 RB40B_HUMAN (1-281): 7.92e-101: 297: 78.65		RBX2_HUMAN (1-113): 1.25e-33: 114: 100.00
+	Sc
		350926 YPT1_YEAST (7-197): 1.86e-84: 253: 35.92		RBX1_YEAST (6-113): 1.27e-35: 119: 41.44
+	Hs
		895518 RAB10_HUMAN (9-197): 1.9e-95: 280: 40.61		RN149_HUMAN (44-112): 2.28e-17: 77.5: 24.64
+	Hs
		894771 RAB8A_HUMAN (7-195): 2.2e-89: 265: 43.16		RN149_HUMAN (44-112): 2.28e-17: 77.5: 24.64
+	Hs
		918908 RAB1A_HUMAN (4-197): 1.67e-87: 261: 36.59		RN149_HUMAN (44-112): 2.28e-17: 77.5: 24.64
+	Hs
		914222 RB11A_HUMAN (4-229): 4.3e-87: 260: 31.72		RN149_HUMAN (44-112): 2.28e-17: 77.5: 24.64
+	Hs
		1240767 RAB1B_HUMAN (7-197): 6.3e-85: 254: 36.32		RN149_HUMAN (44-112): 2.28e-17: 77.5: 24.64
+	Hs
		1079944 RB11B_HUMAN (4-229): 3.23e-84: 253: 32.75		RN149_HUMAN (44-112): 2.28e-17: 77.5: 24.64
+	Hs
		1070305 RAB35_HUMAN (7-197): 1.09e-83: 251: 34.33		RN149_HUMAN (44-112): 2.28e-17: 77.5: 24.64
+	Hs
		886527 RAB15_HUMAN (9-181): 4.62e-46: 155: 44.25		RN149_HUMAN (44-112): 2.28e-17: 77.5: 24.64