Protein: RAB8A
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)

Gene: RAB8A
Organism: Homo sapiens
Interactions: 187
UniProt ID: P61006

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005768 - endosome
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

894790

SYTL4
Synaptotagmin-like protein 4

8

12

Small-scale

0.966

High

678336

GDIA
Rab GDP dissociation inhibitor alpha

6

20

Small-scale

0.949

High

894795

RAB3I
Rab-3A-interacting protein

6

3

Small-scale

0.947

High

838616

GDIB
Rab GDP dissociation inhibitor beta

5

20

Small-scale

0.919

High

894724

OCRL
Inositol polyphosphate 5-phosphatase OCRL

4

9

Small-scale

0.913

High

812735

MSS4
Guanine nucleotide exchange factor MSS4

4

9

Small-scale

0.900

High

894745

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

3

9

Small-scale

0.861

High

894715

RAB1A
Ras-related protein Rab-1A

3

20

Small-scale

0.855

High

894787

RAB8B
Ras-related protein Rab-8B

3

19

Small-scale

0.855

High

894777

R3GEF
Guanine nucleotide exchange factor for Rab-3A

3

3

Small-scale

0.849

High

894788

RIPL2
RILP-like protein 2

2

6

Small-scale

0.825

High

894763

MILK2
MICAL-like protein 2

3

20

Small-scale

0.818

High

894828

RP3A
Rabphilin-3A

2

11

High-throughput

0.811

High

894754

MICA3
[F-actin]-monooxygenase MICAL3

3

20

Small-scale

0.802

High

894709

RAB10
Ras-related protein Rab-10

2

19

High-throughput

0.776

High

894744

RIPL1
RILP-like protein 1

2

10

Small-scale

0.767

High

894825

MYO5B
Unconventional myosin-Vb

2

9

Small-scale

0.757

High

894791

OPTN
Optineurin

7

18

Small-scale

0.743

High

894727

TBC8B
TBC1 domain family member 8B

2

14

Small-scale

0.735

High

894734

RB39A
Ras-related protein Rab-39A

2

20

Small-scale

0.735

High

894767

MILK1
MICAL-like protein 1

2

20

Small-scale

0.735

High

894779

MICA1
[F-actin]-monooxygenase MICAL1

2

20

Small-scale

0.735

High

894728

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

8

Small-scale

0.713

High

685333

I5P2
Type II inositol 1,4,5-trisphosphate 5-phosphatase

2

9

Small-scale

0.712

High

894809

TBC17
TBC1 domain family member 17

1

19

Small-scale

0.691

High

894833

SRPRB
Signal recognition particle receptor subunit beta

3

20

High-throughput

0.667

High

803468

BAG6
Large proline-rich protein BAG6

3

7

Small-scale

0.658

High

894747

TBC9B
TBC1 domain family member 9B

2

15

Small-scale

0.658

High

894758

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.656

High

845844

RAB13
Ras-related protein Rab-13

1

17

Small-scale

0.647

High

894712

RB11A
Ras-related protein Rab-11A

1

18

Small-scale

0.647

High

894835

STK24
Serine/threonine-protein kinase 24

1

5

Small-scale

0.647

High

792758

EAA3
Excitatory amino acid transporter 3

2

3

High-throughput

0.628

High

894766

EH1L1
EH domain-binding protein 1-like protein 1

1

20

Small-scale

0.625

High

894773

EHBP1
EH domain-binding protein 1

1

20

Small-scale

0.625

High

364224

TFR1
Transferrin receptor protein 1

2

1

Small-scale

0.624

High

894813

MYO5C
Unconventional myosin-Vc

1

9

Small-scale

0.621

High

120371

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

373973

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

9

High-throughput

0.618

High

436230

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

505600

EPB41
Protein 4.1

1

5

High-throughput

0.618

High

545295

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564466

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

591536

RAB3B
Ras-related protein Rab-3B

1

17

Small-scale

0.618

High

852418

RND2
Rho-related GTP-binding protein RhoN

1

19

High-throughput

0.618

High

892297

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

893847

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

894710

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

894714

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

894716

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

894720

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

894729

STK4
Serine/threonine-protein kinase 4

1

7

High-throughput

0.618

High

894737

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

894752

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

894762

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.618

High

894789

MIB2
E3 ubiquitin-protein ligase MIB2

1

3

Small-scale

0.618

High

894794

FMNL2
Formin-like protein 2

1

4

High-throughput

0.618

High

894804

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

894811

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

894820

PD1L1
Programmed cell death 1 ligand 1

1

12

Small-scale

0.618

High

894822

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.618

High

894776

EXOC6
Exocyst complex component 6

2

2

Small-scale

0.611

High

229651

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

2

10

Small-scale

0.588

High

894732

SQSTM
Sequestosome-1

2

4

Small-scale

0.584

High

150930

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

2

Small-scale

0.575

High

592647

RAB6A
Ras-related protein Rab-6A

1

19

Small-scale

0.575

High

622570

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

20

Small-scale

0.575

High

642718

RAE2
Rab proteins geranylgeranyltransferase component A 2

1

20

Small-scale

0.575

High

894736

ACAP2
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

1

4

Small-scale

0.575

High

894803

RAB6C
Ras-related protein Rab-6C

1

20

Small-scale

0.575

High

894812

RAB18
Ras-related protein Rab-18

1

19

Small-scale

0.575

High

59692

WDR91
WD repeat-containing protein 91

2

4

Small-scale

0.570

High

894741

WDR81
WD repeat-containing protein 81

2

7

Small-scale

0.570

High

894793

CI072
Guanine nucleotide exchange factor C9orf72

1

2

Small-scale

0.561

High

894759

M4K3
Mitogen-activated protein kinase kinase kinase kinase 3

1

8

Small-scale

0.559

High

894751

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.553

High

130043

EXOC5
Exocyst complex component 5

1

1

High-throughput

0.536

High

646158

STOM
Stomatin

1

4

High-throughput

0.536

High

813293

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

894721

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.536

High

894829

GOT1B
Vesicle transport protein GOT1B

1

1

High-throughput

0.536

High

894831

SAM50
Sorting and assembly machinery component 50 homolog

1

1

High-throughput

0.536

High

552382

RFA2
Replication protein A 32 kDa subunit

2

7

High-throughput

0.533

High

650829

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

8

High-throughput

0.533

High

720114

RFA3
Replication protein A 14 kDa subunit

2

5

High-throughput

0.533

High

538180

ENPL
Endoplasmin

1

4

High-throughput

0.515

High

894768

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.514

High

894778

TBC15
TBC1 domain family member 15

1

19

Small-scale

0.514

High

894749

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.513

High

894775

BBS1
Bardet-Biedl syndrome 1 protein

1

0

High-throughput

0.513

High

894815

CENPM
Centromere protein M

1

0

High-throughput

0.513

High

894818

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.513

High

894743

ODFP2
Outer dense fiber protein 2

1

0

Small-scale

0.504

High

894765

SYTL1
Synaptotagmin-like protein 1

1

11

Small-scale

0.501

High

894836

NEMO
NF-kappa-B essential modulator

1

16

Small-scale

0.501

High

894723

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.500

High

894834

WIF1
Wnt inhibitory factor 1

1

2

High-throughput

0.489

High

80917

B6ZDN3
Doublecortin domain containing 1

1

0

Small-scale

0.480

High

155316

NRP1
Neuropilin-1

1

5

High-throughput

0.479

High

166689

CE290
Centrosomal protein of 290 kDa

1

12

Small-scale

0.479

High

183362

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

1

Small-scale

0.479

High

196287

PJA2
E3 ubiquitin-protein ligase Praja-2

1

12

Small-scale

0.479

High

322400

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

345383

FOS
Protein c-Fos

1

4

High-throughput

0.479

High

377213

GCR
Glucocorticoid receptor

1

12

High-throughput

0.479

High

456838

FURIN
Furin

1

2

High-throughput

0.479

High

507934

FGFR1
Fibroblast growth factor receptor 1

1

5

Small-scale

0.479

High

509578

UBL4A
Ubiquitin-like protein 4A

1

13

High-throughput

0.479

High

525888

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.479

High

666566

LTK
Leukocyte tyrosine kinase receptor

1

15

High-throughput

0.479

High

726122

BASI
Basigin

1

7

High-throughput

0.479

High

742177

SYUA
Alpha-synuclein

1

4

Small-scale

0.479

High

817852

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

827891

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

6

High-throughput

0.479

High

882205

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.479

High

894722

VIGLN
Vigilin

1

1

High-throughput

0.479

High

894726

CALD1
Caldesmon

1

15

High-throughput

0.479

High

894730

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

10

High-throughput

0.479

High

894731

STX3
Syntaxin-3

1

8

Small-scale

0.479

High

894733

DCTN1
Dynactin subunit 1

1

3

High-throughput

0.479

High

894735

TNIP1
TNFAIP3-interacting protein 1

1

16

High-throughput

0.479

High

894738

VAMP3
Vesicle-associated membrane protein 3

1

13

Small-scale

0.479

High

894740

DDR2
Discoidin domain-containing receptor 2

1

16

High-throughput

0.479

High

894746

CP135
Centrosomal protein of 135 kDa

1

2

High-throughput

0.479

High

894748

CDC73
Parafibromin

1

3

High-throughput

0.479

High

894750

RBP10
Ran-binding protein 10

1

2

High-throughput

0.479

High

894753

MAEA
E3 ubiquitin-protein transferase MAEA

1

5

High-throughput

0.479

High

894756

CNTRL
Centriolin

1

6

High-throughput

0.479

High

894760

CEP97
Centrosomal protein of 97 kDa

1

6

High-throughput

0.479

High

894770

POC5
Centrosomal protein POC5

1

1

High-throughput

0.479

High

894774

FLCN
Folliculin

1

3

Small-scale

0.479

High

894780

SMCR8
Guanine nucleotide exchange protein SMCR8

1

2

Small-scale

0.479

High

894782

CLC4D
C-type lectin domain family 4 member D

1

9

High-throughput

0.479

High

894783

RFFL
E3 ubiquitin-protein ligase rififylin

1

6

Small-scale

0.479

High

894785

AKAP1
A-kinase anchor protein 1, mitochondrial

1

5

High-throughput

0.479

High

894792

RMD5B
E3 ubiquitin-protein transferase RMND5B

1

4

High-throughput

0.479

High

894796

RANB9
Ran-binding protein 9

1

2

High-throughput

0.479

High

894797

KIF2C
Kinesin-like protein KIF2C

1

3

Small-scale

0.479

High

894801

FACD2
Fanconi anemia group D2 protein

1

10

High-throughput

0.479

High

894802

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

6

Small-scale

0.479

High

894806

RNF41
E3 ubiquitin-protein ligase NRDP1

1

6

Small-scale

0.479

High

894807

WDR26
WD repeat-containing protein 26

1

5

High-throughput

0.479

High

894814

BIRC6
Baculoviral IAP repeat-containing protein 6

1

6

Small-scale

0.479

High

894817

GID8
Glucose-induced degradation protein 8 homolog

1

5

High-throughput

0.479

High

894819

MTMR4
Myotubularin-related protein 4

1

6

High-throughput

0.479

High

894826

CLC4E
C-type lectin domain family 4 member E

1

9

High-throughput

0.479

High

894827

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

11

Small-scale

0.479

High

894713

YPEL5
Protein yippee-like 5

1

0

High-throughput

0.458

High

894761

LAX1
Lymphocyte transmembrane adapter 1

1

0

Small-scale

0.458

High

894764

EXOC8
Exocyst complex component 8

1

0

High-throughput

0.458

High

894799

TALD3
Protein TALPID3

1

0

Small-scale

0.458

High

894810

CYBP
Calcyclin-binding protein

1

0

Small-scale

0.458

High

894823

MKLN1
Muskelin

1

0

High-throughput

0.458

High

894800

KLF16
Krueppel-like factor 16

1

3

High-throughput

0.457

High

299875

ERLN2
Erlin-2

1

3

Small-scale

0.445

High

574637

ARF4
ADP-ribosylation factor 4

1

19

Small-scale

0.445

High

776089

ARL1
ADP-ribosylation factor-like protein 1

1

20

Small-scale

0.445

High

863088

PGTB2
Geranylgeranyl transferase type-2 subunit beta

1

2

Small-scale

0.445

High

894718

ARF1
ADP-ribosylation factor 1

1

18

Small-scale

0.445

High

894719

ARF5
ADP-ribosylation factor 5

1

18

Small-scale

0.445

High

894769

CD177
CD177 antigen

1

5

Small-scale

0.445

High

894772

MOT11
Monocarboxylate transporter 11

1

7

High-throughput

0.445

High

894784

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

9

Small-scale

0.445

High

894786

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

6

Small-scale

0.445

High

894805

EHD1
EH domain-containing protein 1

1

6

Small-scale

0.445

High

894816

ARL8B
ADP-ribosylation factor-like protein 8B

1

18

Small-scale

0.445

High

894821

VAPA
Vesicle-associated membrane protein-associated protein A

1

3

Small-scale

0.445

High

894824

PPM1H
Protein phosphatase 1H

1

5

Small-scale

0.445

High

241866

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.438

High

303070

HEXI1
Protein HEXIM1

1

6

High-throughput

0.437

High

390804

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

3

High-throughput

0.437

High

823782

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.437

High

894711

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.437

High

894717

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

894755

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

894757

GOLI
E3 ubiquitin-protein ligase RNF130

1

15

High-throughput

0.437

High

894771

RN149
E3 ubiquitin-protein ligase RNF149

1

14

High-throughput

0.437

High

894808

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

4

High-throughput

0.437

High

266136

ERLN1
Erlin-1

1

1

Small-scale

0.407

High

894725

TAGL
Transgelin

1

3

High-throughput

0.407

High

894798

ESYT1
Extended synaptotagmin-1

1

6

Small-scale

0.407

High

311227

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

0

High-throughput

0.279

Low

894739

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

0

High-throughput

0.279

Low

894781

SSMM1
Serine-rich single-pass membrane protein 1

1

0

High-throughput

0.279

Low

894742

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.249

Low

894830

RIPR2
Rho family-interacting cell polarization regulator 2

1

0

High-throughput

0.249

Low

894832

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024