HitPredict

Interactor 1: GCN5 (Q9AR19)
Histone acetyltransferase GCN5 (AtGCN5) (EC 2.3.1.48) (BIG TOP protein)
Gene: HAG1

Interactor 2: TAD2B (Q9ATB4)
Transcriptional adapter ADA2b (AtADA2b) (Protein PROPORZ 1)
Gene: ADA2B

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.908

Property	Details
Experiments	16603259, 11266554, 18498779, 21798944
Identification Methods	enzymatic study, pull down, two hybrid, two hybrid array
Interaction Type	direct interaction, physical association, acetylation reaction

Property	Details
Interacting Pfam domains	Acetyltransf_1~Myb_DNA-binding
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 568 At			1 487
+	At
		1308015 GCN5_ARATH (1-568): 0: 627: 100.00		TAD2A_ARATH (1-485): 1.34e-149: 440: 43.49
+	Hs
		266399 KAT2B_HUMAN (78-559): 1.04e-173: 514: 33.06		TAD2A_HUMAN (40-483): 2.57e-125: 374: 27.90
+	Mm
		1208540 KAT2B_MOUSE (82-559): 1.62e-175: 518: 34.16		TAD2A_MOUSE (40-483): 1.6e-123: 369: 28.76
+	Hs
		266398 KAT2A_HUMAN (119-559): 1.5e-167: 499: 35.90		TAD2A_HUMAN (40-483): 2.57e-125: 374: 27.90
+	Sc
		970392 GCN5_YEAST (74-562): 1.13e-164: 477: 38.90		ADA2_YEAST (42-479): 5.96e-132: 390: 27.98
+	Mm
		1208541 KAT2A_MOUSE (119-559): 5.31e-165: 492: 36.28		TAD2A_MOUSE (40-483): 1.6e-123: 369: 28.76
+	Hs
		1198566 KAT2B_HUMAN (78-559): 1.04e-173: 514: 33.06		TAD2B_HUMAN (39-475): 3.53e-113: 342: 25.66
+	Hs
		1198565 KAT2A_HUMAN (119-559): 1.5e-167: 499: 35.90		TAD2B_HUMAN (39-475): 3.53e-113: 342: 25.66
+	Dm
		1181824 Q9VTZ1_DROME (87-560): 2.57e-172: 510: 33.61		TAD2A_DROME (31-483): 2.8e-105: 326: 23.63
+	Dm
		283712 O76216_DROME (87-560): 1.08e-171: 508: 33.40		TAD2A_DROME (31-483): 2.8e-105: 326: 23.63
+	Dm
		1212009 Q9VTZ1_DROME (87-560): 2.57e-172: 510: 33.61		TAD2B_DROME (35-412): 5.13e-89: 284: 25.51
+	Dm
		283714 O76216_DROME (87-560): 1.08e-171: 508: 33.40		TAD2B_DROME (35-412): 5.13e-89: 284: 25.51
+	Sc
		797934 GCN5_YEAST (74-562): 1.13e-164: 477: 38.90		RSC8_YEAST (29-308): 6.91e-50: 180: 18.86
+	Sc
		696166 GCN5_YEAST (74-562): 1.13e-164: 477: 38.90		SWI3_YEAST (101-346): 2.68e-35: 142: 17.60
+	Sc
		715378 SPT7_YEAST (310-561): 9.23e-43: 166: 14.45		ADA2_YEAST (42-479): 5.96e-132: 390: 27.98
+	Pf
		1211774 Q8IB67_PLAF7 (196-565): 1.04e-131: 420: 42.70		Q8I5G5_PLAF7 (9-187): 4.94e-32: 132: 14.89
+	Sc
		715346 SPT7_YEAST (310-561): 9.23e-43: 166: 14.45		RSC8_YEAST (29-308): 6.91e-50: 180: 18.86
+	Sc
		696128 SPT7_YEAST (310-561): 9.23e-43: 166: 14.45		SWI3_YEAST (101-346): 2.68e-35: 142: 17.60
+	Hs
		998902 EP300_HUMAN (362-563): 1.31e-40: 160: 19.02		SMRC2_HUMAN (119-360): 1.02e-36: 146: 16.94
+	Hs
		998950 EP300_HUMAN (362-563): 1.31e-40: 160: 19.02		SMRC1_HUMAN (102-309): 5.13e-28: 120: 16.11