HitPredict

Interactor 1: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Interactor 2: RIOK1 (Q9BRS2)
Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)
Gene: RIOK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.724

Property	Details
Experiments	28977470, 21081503, 25852190, 35271311, 32707033
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 342 Hs			1 568
+	Hs
		1281350 FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29		RIOK1_HUMAN (1-568): 0: 673: 100.00
+	Hs
		1240451 POC1A_HUMAN (201-341): 1.98e-27: 112: 18.31		RIOK1_HUMAN (1-568): 0: 673: 100.00
+	Hs
		197079 PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40		RIOK1_HUMAN (1-568): 0: 673: 100.00
+	Dm
		1279325 EBI_DROME (161-342): 6.92e-30: 122: 15.98		Q9VR42_DROME (4-519): 3.35e-134: 405: 25.32
+	Sc
		744714 TAF5_YEAST (15-267): 2.96e-38: 146: 14.77		RIO1_YEAST (109-546): 5.16e-116: 354: 36.56
+	Sc
		784446 COPB2_YEAST (15-314): 1.99e-22: 100: 14.47		RIO1_YEAST (109-546): 5.16e-116: 354: 36.56