Interactor 1: APC13 (Q9BS18)
Anaphase-promoting complex subunit 13 (APC13) (Cyclosome subunit 13)
Gene: ANAPC13

Interactor 2: CDC23 (Q9UJX2)
Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)
Gene: CDC23

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 25416956, 26496610, 32296183, 35271311, 28514442, 33961781, unassigned1304, 20360068
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach, tandem affinity purification, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC8~Apc13p, Apc13p~TPR_8
Common GO terms GO:0005680 - anaphase-promoting complex
GO:0007346 - regulation of mitotic cell cycle
GO:0031145 - anaphase-promoting complex-dependent catabolic process
GO:0051301 - cell division
GO:0051445 - regulation of meiotic cell cycle
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 74
Hs

1 597
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024