HitPredict

Interactor 1: DIDO1 (Q9BTC0)
Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)
Gene: DIDO1

Interactor 2: TPX2 (Q9ULW0)
Targeting protein for Xklp2 (Differentially expressed in cancerous and non-cancerous lung cells 2) (DIL-2) (Hepatocellular carcinoma-associated antigen 519) (Hepatocellular carcinoma-associated antigen 90) (Protein fls353) (Restricted expression proliferation-associated protein 100) (p100)
Gene: TPX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005819 - spindle
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2240 Hs			1 747
+	Hs
		833053 YLPM1_HUMAN (1365-2223): 2.36e-41: 170: 13.66		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		1017366 BPTF_HUMAN (82-420): 9.56e-40: 165: 14.29		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		1327750 NSRP1_HUMAN (2033-2240): 4.74e-23: 108: 18.27		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		1300996 CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		1267654 PHF3_HUMAN (1921-2190): 3.11e-09: 64.7: 14.29		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Dm
		1376672 FUTSC_DROME (2-1740): 1.48e-32: 141: 10.60		FUTSC_DROME (37-705): 3.03e-10: 66.4: 11.95
+	Dm
		65570 FUTSC_DROME (2-1740): 1.48e-32: 141: 10.60		A8JNM5_DROME (60-735): 3.81e-09: 62.6: 11.77
+	Hs
		1264771 TITIN_HUMAN (19-1290): 3.32e-21: 104: 10.49		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Dm
		113976 M9PB30_DROME (42-789): 3.1e-10: 68.3: 8.80		M9PB30_DROME (191-729): 3.7e-14: 79.1: 8.07