HitPredict

Interactor 1: MED10 (Q9BTT4)
Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (Transformation-related gene 17 protein) (TRG-17) (Transformation-related gene 20 protein) (TRG-20)
Gene: MED10

Interactor 2: CDK19 (Q9BWU1)
Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)
Gene: CDK19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	15175163, 24981860, 33961781, 26186194, 28514442, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 135 Hs			1 502
+	Hs
		826345 MED10_HUMAN (1-135): 2.83e-61: 186: 100.00		CDK8_HUMAN (1-502): 1.77e-150: 439: 76.69
+	Hs
		73039 MED10_HUMAN (1-135): 2.83e-61: 186: 100.00		B4DUB1_HUMAN (152-502): 1.59e-138: 406: 100.00
+	Sc
		760593 MED10_YEAST (1-133): 5.12e-35: 120: 25.18		SSN3_YEAST (41-376): 4.15e-75: 248: 43.64